Distribution and high frequency of novel alleles at NF1 polymorphic markers in the Italian population

• Published in: Molecular and cellular probes Vol. 13; no. 6; pp. 415 - 420
• Main Authors: Natacci, F, Colapietro, P, Riva, P, Corrado, L, Rossi, LN, Maninetti, MM, Casciati, MC, Zambrino, CA, Lanzi, Larizza, L
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.1999
• Subjects: Alleles; Biomarkers, Tumor; Female; Gene Frequency; Genes, Neurofibromatosis 1 - genetics; Genetic Markers; Humans; Italy - epidemiology; Male; Neurofibromatosis 1 - epidemiology; Neurofibromatosis 1 - genetics; neurofibromatosis type 1, intragenic DNA polymorphisms, mutation rate, allele frequencies; Pedigree; Polymorphism, Genetic; Italy; neurofibromatosis type 1, intragenic DNA polymorphisms, mutation rate, allele frequencies

Segregation analysis of Neurofibromatosis type 1 (NF1) intragenic polymorphisms is a useful diagnostic tool for linkage analysis in familial cases and for the exclusion/detection of deletion in sporadic patients. We performed a segregation analysis of intragenic NF1 polymorphic markers in an Italian...