Insulin rapidly upregulates protein kinase Cδ gene expression in skeletal muscle

• Published in: Cellular signalling Vol. 18; no. 2; pp. 183 - 193
• Main Authors: Horovitz-Fried, Miriam, Cooper, Denise R., Patel, Niketa A., Cipok, Michal, Brand, Chagit, Bak, Asia, Inbar, Aya, Jacob, Avraham I., Sampson, Sanford R.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.02.2006
• Subjects: Degradation; Expression; Gene transcription; Immediate early response gene; Degradation; Immediate early response gene; Expression; Gene transcription

Recent studies in our laboratories have shown that Protein Kinase C delta (PKCδ) is essential for insulin-induced glucose transport in skeletal muscle, and that insulin rapidly stimulates PKCδ activity skeletal muscle. The purpose of this study was to examine mechanisms of regulation of PKCδ protein...