Relationship of carcinogen-induced sister chromatid exchange and neoplastic cell transformation

• Published in: International journal of cancer Vol. 28; no. 1; p. 71
• Main Authors: Popescu, N C, Amsbaugh, S C, DiPaolo, J A
• Format: Journal Article
• Language: English
• Published: United States 15.07.1981
• Subjects: Acetoxyacetylaminofluorene - pharmacology; Animals; Benzopyrenes - pharmacology; Carcinogens - pharmacology; Cell Transformation, Neoplastic; Cells, Cultured; Cisplatin - pharmacology; Cricetinae; Crossing Over, Genetic - drug effects; Dose-Response Relationship, Drug; In Vitro Techniques; Mesocricetus; Methyl Methanesulfonate - pharmacology; Methylnitronitrosoguanidine - pharmacology; Neoplasms, Radiation-Induced - etiology; Sister Chromatid Exchange - drug effects

Sister chromatid exchange (SCE) and morphological transformation induced by five chemical carcinogens, N-acetoxy-2-fluorenyl-acetamide (AcAAF), N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), methyl methanesulfonate (MMS), benzo[a]-pyrene (BP), and cisplatinum(II) diamine dichloride (PT) as well a...