Gastrointestinal dysbiosis following diethylhexyl phthalate exposure in zebrafish (Danio rerio): Altered microbial diversity, functionality, and network connectivity
Microbiome community structure is intimately involved in key biological functions in the gastrointestinal (GI) system including nutrient absorption and lipid metabolism. Recent evidence suggests that disruption of the GI microbiome is a contributing factor to metabolic disorders and obesity. Poor di...
Saved in:
Published in | Environmental pollution (1987) Vol. 265; p. 114496 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier Ltd
01.10.2020
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Microbiome community structure is intimately involved in key biological functions in the gastrointestinal (GI) system including nutrient absorption and lipid metabolism. Recent evidence suggests that disruption of the GI microbiome is a contributing factor to metabolic disorders and obesity. Poor diet and chemical exposure have been independently shown to cause disruption of the GI microbiome community structure and function. We hypothesized that the addition a chemical exposure to overfeeding exacerbates adverse effects on the GI microbiome community structure and function. To test this hypothesis, adult zebrafish were fed a normal feeding regime (Control), an overfeeding regime (OF), or an overfeeding regime contaminated with diethylhexyl phthalate (OF + DEHP), a suspected obesogen-inducing chemical. After 60 days, fecal matter was collected for sequencing, identification, and quantification of the GI microbiome using the 16s rRNA hypervariable region. Analysis of beta diversity indicated distinct microbial profiles between treatments with the largest divergence between Control and OF + DEHP groups. Based upon functional predictions, OF + DEHP treatment altered carbohydrate metabolism, while both OF and OF + DEHP affected biosynthesis of fatty acids and lipid metabolism. Co-occurrence network analysis revealed decreases in cluster size and a fracturing of the microbial community network into unconnected components and a loss of keystone species in the OF + DEHP treatment when compared to Control and OF treatments. Data suggest that the addition of DEHP in the diet may exacerbate microbial dysbiosis, a consequence that may explain in part its role as an obesogenic chemical.
[Display omitted]
•Zebrafish were co-exposed to overfeeding and diethylhexyl phthalate (DEHP).•Microbial profiles were distinct following co-exposure or overfeeding alone.•Predicted microbial functional profiles differed between treatment groups.•Microbial networks were fragmented following overfeeding with DEHP.
Co-treatment of overfeeding with DEHP results in distinct microbial profiles characterized by alterations in diversity, function, and microbial network ecology, which may contribute to obesogenic mechanisms in the host. |
---|---|
AbstractList | Microbiome community structure is intimately involved in key biological functions in the gastrointestinal (GI) system including nutrient absorption and lipid metabolism. Recent evidence suggests that disruption of the GI microbiome is a contributing factor to metabolic disorders and obesity. Poor diet and chemical exposure have been independently shown to cause disruption of the GI microbiome community structure and function. We hypothesized that the addition a chemical exposure to overfeeding exacerbates adverse effects on the GI microbiome community structure and function. To test this hypothesis, adult zebrafish were fed a normal feeding regime (Control), an overfeeding regime (OF), or an overfeeding regime contaminated with diethylhexyl phthalate (OF + DEHP), a suspected obesogen-inducing chemical. After 60 days, fecal matter was collected for sequencing, identification, and quantification of the GI microbiome using the 16s rRNA hypervariable region. Analysis of beta diversity indicated distinct microbial profiles between treatments with the largest divergence between Control and OF + DEHP groups. Based upon functional predictions, OF + DEHP treatment altered carbohydrate metabolism, while both OF and OF + DEHP affected biosynthesis of fatty acids and lipid metabolism. Co-occurrence network analysis revealed decreases in cluster size and a fracturing of the microbial community network into unconnected components and a loss of keystone species in the OF + DEHP treatment when compared to Control and OF treatments. Data suggest that the addition of DEHP in the diet may exacerbate microbial dysbiosis, a consequence that may explain in part its role as an obesogenic chemical.
[Display omitted]
•Zebrafish were co-exposed to overfeeding and diethylhexyl phthalate (DEHP).•Microbial profiles were distinct following co-exposure or overfeeding alone.•Predicted microbial functional profiles differed between treatment groups.•Microbial networks were fragmented following overfeeding with DEHP.
Co-treatment of overfeeding with DEHP results in distinct microbial profiles characterized by alterations in diversity, function, and microbial network ecology, which may contribute to obesogenic mechanisms in the host. |
ArticleNumber | 114496 |
Author | Buerger, Amanda N. Yang, Tao Bisesi, Joseph H. Dillon, David T. Schmidt, Jordan Zubcevic, Jasenka Martyniuk, Christopher J. |
Author_xml | – sequence: 1 givenname: Amanda N. surname: Buerger fullname: Buerger, Amanda N. organization: Department of Environmental and Global Health, University of Florida, Gainesville, FL, USA – sequence: 2 givenname: David T. surname: Dillon fullname: Dillon, David T. organization: Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, USA – sequence: 3 givenname: Jordan surname: Schmidt fullname: Schmidt, Jordan organization: Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, USA – sequence: 4 givenname: Tao surname: Yang fullname: Yang, Tao organization: The Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, OH, USA – sequence: 5 givenname: Jasenka surname: Zubcevic fullname: Zubcevic, Jasenka organization: Department of Physiological Sciences, University of Florida, Gainesville, FL, USA – sequence: 6 givenname: Christopher J. surname: Martyniuk fullname: Martyniuk, Christopher J. organization: Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, USA – sequence: 7 givenname: Joseph H. surname: Bisesi fullname: Bisesi, Joseph H. email: jbisesi@phhp.ufl.edu organization: Department of Environmental and Global Health, University of Florida, Gainesville, FL, USA |
BookMark | eNp9UctuFDEQtFCQ2AT-gIOPQWIWv-bFASkKEJAicYGz5Rn3ML147cX2bjL8D_-Jl-HMqdVd3V2qqkty4YMHQl5ytuWMN292W_CnQ3BbwUQZcaX65gnZ8K6VVaOEuiAbJpq-alXPn5HLlHaMMSWl3JDfdyblGNBnSBm9cdQuacCQMNEpOBce0H-nFiHPi5vhcXH0MOfZOJOBwuMhpGMEip7-giGaCdNMr98bj4FGiBhevaU3LkMES_c4xjDgmQFPEBPm5TWdjn7MGArv39Z4Sz3khxB_0DF4DwU8FeQ5eToZl-DFv3pFvn388PX2U3X_5e7z7c19NUrZ56rrjRWtbARXYmxtX7POwmSZbPueTYMU0HTDYBUI2QphRd3yrulNLYysix-TvCLX699DDD-PxRG9xzSCc8ZDOCYtlKyLqy1vyqpaV4uqlCJM-hBxb-KiOdPnVPROr6nocyp6TaWcvVvPoMg4IUSdRgQ_gsVY1Gob8P8P_gDE455O |
CitedBy_id | crossref_primary_10_1038_s41598_021_03238_3 crossref_primary_10_1017_gmb_2023_3 crossref_primary_10_2903_fr_efsa_2023_FR_0011 crossref_primary_10_1016_j_jhazmat_2022_129996 crossref_primary_10_1371_journal_pone_0269137 crossref_primary_10_1007_s11356_022_22327_y crossref_primary_10_1007_s11906_022_01226_0 crossref_primary_10_1016_j_scitotenv_2020_141724 crossref_primary_10_3390_toxics9090215 crossref_primary_10_1016_j_ecoenv_2021_112716 crossref_primary_10_3390_ijms25010675 crossref_primary_10_1152_physiolgenomics_00013_2024 crossref_primary_10_3389_fphys_2023_1186645 crossref_primary_10_1016_j_coemr_2021_05_006 crossref_primary_10_1016_j_chemosphere_2022_135703 crossref_primary_10_1021_acs_jafc_2c03864 crossref_primary_10_1016_j_bcp_2022_115015 crossref_primary_10_1016_j_cbd_2022_100993 crossref_primary_10_1016_j_cbpc_2024_109956 crossref_primary_10_1016_j_scitotenv_2021_150963 crossref_primary_10_3389_fimmu_2022_916100 crossref_primary_10_1016_j_cbd_2021_100834 crossref_primary_10_1016_j_ygcen_2020_113437 crossref_primary_10_1038_s41559_022_01746_7 |
Cites_doi | 10.1371/journal.pone.0143190 10.1007/s12020-016-1158-4 10.1289/ehp.1104597 10.1016/j.mce.2009.02.017 10.1016/j.fct.2012.04.029 10.1016/j.ijheh.2006.09.005 10.1186/s40168-016-0173-2 10.1186/s13059-015-0614-4 10.1073/pnas.1113246109 10.1161/CIRCRESAHA.115.306807 10.1016/j.clim.2015.05.013 10.3389/fmicb.2014.00219 10.1371/journal.pone.0024455 10.1016/j.ajog.2016.01.182 10.1177/0884533611436116 10.1016/j.taap.2009.02.008 10.1002/oby.21359 10.1093/toxsci/kfy261 10.1371/journal.pone.0010201 10.1093/toxsci/kfy205 10.1016/j.cmet.2013.05.004 10.1007/s11154-007-9049-x 10.1194/jlr.M002774 10.1016/j.endonu.2011.11.008 10.1038/nbt.2676 10.1096/fj.13-231670 10.1038/ijo.2008.207 10.1101/gad.212522.112 10.1053/jhep.2003.50446 10.1042/BSR20120042 10.1038/ismej.2011.38 10.1371/journal.pone.0154632 10.1080/19490976.2015.1134082 10.1016/j.dci.2016.02.020 10.1016/j.chom.2015.04.009 10.1152/physiolgenomics.00034.2016 10.1007/s00244-005-5089-y 10.3389/fmicb.2018.01323 10.1289/ehp.9882 10.1242/dmm.011346 10.1016/j.chom.2012.08.003 10.1016/j.jnutbio.2017.04.001 10.1186/s13073-015-0157-z 10.3389/fmicb.2016.00409 10.1002/9780471729259.mc01e05s27 10.1161/HYPERTENSIONAHA.115.05315 10.1038/s41579-018-0024-1 10.1016/j.socnet.2014.06.001 10.1089/107555302317371479 10.1007/s10916-019-1172-1 10.1016/j.envpol.2018.11.032 10.1186/1472-6793-10-21 10.1289/ehp.0901217 10.1186/s12866-017-1027-1 10.1111/cmi.12308 10.1021/acs.chemrestox.6b00066 10.1016/j.chemosphere.2017.09.123 10.1038/nrmicro3344 10.1136/jech-2015-206315 10.1093/bioinformatics/btu494 10.1111/j.1365-2982.2012.01895.x 10.1016/j.envres.2017.09.004 10.1038/ijo.2015.8 10.3109/10408444.2013.860076 10.1038/s41467-017-01944-z 10.1111/jgh.14059 10.1053/j.gastro.2009.02.075 10.1093/toxsci/kfy102 |
ContentType | Journal Article |
Copyright | 2020 Elsevier Ltd |
Copyright_xml | – notice: 2020 Elsevier Ltd |
DBID | AAYXX CITATION 7X8 |
DOI | 10.1016/j.envpol.2020.114496 |
DatabaseName | CrossRef MEDLINE - Academic |
DatabaseTitle | CrossRef MEDLINE - Academic |
DatabaseTitleList | |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Engineering Anatomy & Physiology Environmental Sciences |
EISSN | 1873-6424 |
EndPage | 114496 |
ExternalDocumentID | 10_1016_j_envpol_2020_114496 S0269749119345737 |
GroupedDBID | --- --K --M -~X .~1 0R~ 1B1 1RT 1~. 29G 4.4 457 53G 5GY 5VS 6TJ 71M 8P~ 9JM AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXUO ABEFU ABFNM ABFYP ABJNI ABLST ABMAC ABXDB ABYKQ ACDAQ ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD AEBSH AEKER AENEX AFFNX AFKWA AFTJW AFXIZ AGHFR AGUBO AGYEJ AHEUO AHHHB AI. AIEXJ AIKHN AITUG AJBFU AJOXV AKIFW ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLECG BLXMC CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HLV HMC HVGLF HZ~ IHE J1W KCYFY KOM LW9 LY9 M41 MO0 N9A O-L O9- OAUVE OHT OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SAB SCC SCU SDF SDG SDP SEN SES SEW SPCBC SSJ SSZ T5K TWZ VH1 WH7 WUQ XJT XOL XPP ZMT ~G- AAHBH AAXKI AAYXX ACRPL AFJKZ AKRWK CITATION 7X8 |
ID | FETCH-LOGICAL-c339t-89ad27362142c7d9508defd037990fb32e68bbd4e23722d2571869a52a35043f3 |
IEDL.DBID | .~1 |
ISSN | 0269-7491 |
IngestDate | Wed Dec 04 04:41:51 EST 2024 Fri Dec 06 01:25:26 EST 2024 Fri Feb 23 02:47:03 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Keywords | Obesity Zebrafish Gastrointestinal system Network analysis Phthalates Microbiome |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c339t-89ad27362142c7d9508defd037990fb32e68bbd4e23722d2571869a52a35043f3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PQID | 2435187716 |
PQPubID | 23479 |
PageCount | 1 |
ParticipantIDs | proquest_miscellaneous_2435187716 crossref_primary_10_1016_j_envpol_2020_114496 elsevier_sciencedirect_doi_10_1016_j_envpol_2020_114496 |
PublicationCentury | 2000 |
PublicationDate | October 2020 2020-10-00 20201001 |
PublicationDateYYYYMMDD | 2020-10-01 |
PublicationDate_xml | – month: 10 year: 2020 text: October 2020 |
PublicationDecade | 2020 |
PublicationTitle | Environmental pollution (1987) |
PublicationYear | 2020 |
Publisher | Elsevier Ltd |
Publisher_xml | – name: Elsevier Ltd |
References | Buerger, Schmidt, Chase, Paxaio, Patel, Brumback, Kane, Martyniuk, Bisesi (bib5) 2019; 245 García-Mayor, Vidal, Caamano, Giménez (bib21) 2012; 59 Hansen, Gøbel, Hansen, Pedersen (bib29) 2015; 7 Hunt, Wang, Chen, Wang, Waltz (bib32) 2017; 159 Gaulke, Barton, Proffitt, Tanguay, Sharpton (bib22) 2016; 11 Stienstra, Duval, Müller, Kersten (bib64) 2006; vol. 2007 Norman, Börjeson, David, Tienpont, Norrgren (bib50) 2007; 52 Morrison, Preston (bib47) 2016; 7 Labaronne, Pinteur, Vega, Pesenti, Julien, Meugnier-Fouilloux, Vidal, Naville, Le Magueresse-Battistoni (bib41) 2017; 45 Desvergne, Feige, Casals-Casas (bib15) 2009; 304 Camp, Kanther, Semova, Rawls (bib6) 2009; 136 Pradhan, Olsson, Jass (bib55) 2018; 190 Yang, Santisteban, Rodriguez, Li, Ahmari, Carvajal, Zadeh, Gong, Qi, Zubcevic (bib70) 2015; 65 Petersen, Round (bib53) 2014; 16 Feige, Gerber, Casals-Casas, Yang, Winkler, Bedu, Bueno, Gelman, Auwerx, Gonzalez (bib17) 2010; 118 Hales, Margaret, Carroll, Fryar, Ogden (bib28) 2017; vol. 288 Goodman, LaKind, Mattison (bib23) 2014; 44 Gülden, Wong, Wen (bib25) 2015; 159 Janesick, Blumberg (bib33) 2016; 214 Li, Yang, Jin, Li, Qian, Xiong, Song, Hou (bib43) 2018; 33 Stojanoska, Milosevic, Milic, Abenavoli (bib65) 2017; 55 Kuczynski, Stombaugh, Walters, González, Caporaso, Knight (bib40) 2012; 27 Backhed, Ding, Wang, Hooper, Koh, Nagy, Semenkovich, Gordon (bib1) 2004 Fierens, Servaes, Van Holderbeke, Geerts, De Henauw, Sioen, Vanermen (bib18) 2012; 50 Chi, Bian, Gao, Ru, Tu, Lu (bib11) 2016; 29 Koliada, Syzenko, Moseiko, Budovska, Puchkov, Perederiy, Gavalko, Dorofeyev, Romanenko, Tkach (bib37) 2017; 17 Kostic, Howitt, Garrett (bib38) 2013; 27 Casals-Casas, Feige, Desvergne (bib8) 2008; 32 Hao, Cheng, Xia, Ma (bib30) 2012; 32 Louis, Hold, Flint (bib44) 2014; 12 Selmi, Balkwill, Invernizzi, Ansari, Coppel, Podda, Leung, Kenny, Van De Water, Nantz (bib58) 2003; 38 Zamakhchari, Wei, Dewhirst, Lee, Schuppan, Oppenheim, Helmerhorst (bib71) 2011; 6 Parks, Tyson, Hugenholtz, Beiko (bib52) 2014; 30 Yaghjyan, Sites, Ruan, Chang (bib69) 2015; 39 Hahn-Townsend, Varde, MohanKumar, MohanKumar (bib27) 2016; 30 Semova, Carten, Stombaugh, Mackey, Knight, Farber, Rawls (bib59) 2012; 12 Carnevali, Tosti, Speciale, Peng, Zhu, Maradonna (bib7) 2010; 5 Dahan, Jude, Lamendella, Keesing, Perron (bib14) 2018; 9 Klöting, Hesselbarth, Gericke, Kunath, Biemann, Chakaroun, Kosacka, Kovacs, Kern, Stumvoll (bib36) 2015; 10 Reátegui, Ratté, Bautista-Valarezo, Duque (bib56) 2019; 43 Velagapudi, Hezaveh, Reigstad, Gopalacharyulu, Yetukuri, Islam, Felin, Perkins, Borén, Orešič (bib68) 2010; 51 Banerjee, Schlaeppi, van der Heijden (bib3) 2018; 16 Fu, Bonder, Cenit, Tigchelaar, Maatman, Dekens, Brandsma, Marczynska, Imhann, Weersma (bib20) 2015; 117 Brugman (bib4) 2016; 64 Oka, Nishimura, Zang, Hirano, Shimada, Wang, Umemoto, Kuroyanagi, Nishimura, Tanaka (bib51) 2010; 10 Stecher, Denzler, Maier, Bernet, Sanders, Pickard, Barthel, Westendorf, Krogfelt, Walker (bib63) 2012; 109 Fromme, Bolte, Koch, Angerer, Boehmer, Drexler, Mayer, Liebl (bib19) 2007; 210 Stahlhut, van Wijngaarden, Dye, Cook, Swan (bib62) 2007; 115 Zhou, Tang, Wang, Wang (bib72) 2018; 164 Hacquard, Garrido-Oter, González, Spaepen, Ackermann, Lebeis, McHardy, Dangl, Knight, Ley (bib26) 2015; 17 Thayer, Heindel, Bucher, Gallo (bib67) 2012; 120 Baillie-Hamilton (bib2) 2002; 8 Csardi, Nepusz (bib13) 2006; 1695 Seth, Stemple, Barroso (bib60) 2013; 6 Roeselers, Mittge, Stephens, Parichy, Cavanaugh, Guillemin, Rawls (bib57) 2011; 5 Krajmalnik-Brown, Ilhan, Kang, DiBaise (bib39) 2012; 27 Neal (bib49) 2014; 39 Sommer, Nookaew, Sommer, Fogelstrand, Bäckhed (bib61) 2015; 16 Martín, Bermúdez-Humarán, Langella (bib46) 2016; 7 Chamorro-Garcia, Diaz-Castillo, Shoucri, Käch, Leavitt, Shioda, Blumberg (bib10) 2017; 8 Berry, Widder (bib73) 2014; 5 Hu, Raikhel, Gopalakrishnan, Fernandez-Hernandez, Lambertini, Manservisi, Falcioni, Bua, Belpoggi, Teitelbaum (bib31) 2016; 4 Eveillard, Lasserre, de Tayrac, Polizzi, Claus, Canlet, Mselli-Lakhal, Gotardi, Paris, Guillou (bib16) 2009; 236 Lv, Cheng, Huang, Zhang, Wu, Qiu, Geng, Zhang, Huang, Ma (bib45) 2016; 24 Naville, Pinteur, Vega, Menade, Vigier, Le Bourdais, Labaronne, Debard, Luquain-Costaz, Bégeot (bib48) 2013; 27 Catron, Keely, Brinkman, Zurlinden, Wood, Wright, Phelps, Wheaton, Kvasnicka, Gaballah (bib9) 2018; 167 Langille, Zaneveld, Caporaso, McDonald, Knights, Reyes, Clemente, Burkepile, Thurber, Knight (bib42) 2013; 31 Tehrani, Nezami, Gewirtz, Srinivasan (bib66) 2012; 24 Grün, Blumberg (bib24) 2007; 8 Jin, Zeng, Wang, Luo, Wang, Zhou, Ni, Fu, Jin (bib34) 2018; 166 Cox, Blaser (bib12) 2013; 17 Pfalzer, Kamanu, Parnell, Tai, Liu, Mason, Crott (bib54) 2016; 48 Kim, Park, Lee, Cho, Choi, Choi, Kim, Eun, Suh, Kim (bib35) 2016; 70 Oka (10.1016/j.envpol.2020.114496_bib51) 2010; 10 Gülden (10.1016/j.envpol.2020.114496_bib25) 2015; 159 Baillie-Hamilton (10.1016/j.envpol.2020.114496_bib2) 2002; 8 Morrison (10.1016/j.envpol.2020.114496_bib47) 2016; 7 Chi (10.1016/j.envpol.2020.114496_bib11) 2016; 29 Fromme (10.1016/j.envpol.2020.114496_bib19) 2007; 210 Parks (10.1016/j.envpol.2020.114496_bib52) 2014; 30 Pradhan (10.1016/j.envpol.2020.114496_bib55) 2018; 190 Brugman (10.1016/j.envpol.2020.114496_bib4) 2016; 64 Buerger (10.1016/j.envpol.2020.114496_bib5) 2019; 245 Neal (10.1016/j.envpol.2020.114496_bib49) 2014; 39 Casals-Casas (10.1016/j.envpol.2020.114496_bib8) 2008; 32 Fierens (10.1016/j.envpol.2020.114496_bib18) 2012; 50 Hales (10.1016/j.envpol.2020.114496_bib28) 2017; vol. 288 Stahlhut (10.1016/j.envpol.2020.114496_bib62) 2007; 115 Klöting (10.1016/j.envpol.2020.114496_bib36) 2015; 10 Krajmalnik-Brown (10.1016/j.envpol.2020.114496_bib39) 2012; 27 Carnevali (10.1016/j.envpol.2020.114496_bib7) 2010; 5 Selmi (10.1016/j.envpol.2020.114496_bib58) 2003; 38 Kuczynski (10.1016/j.envpol.2020.114496_bib40) 2012; 27 Gaulke (10.1016/j.envpol.2020.114496_bib22) 2016; 11 Jin (10.1016/j.envpol.2020.114496_bib34) 2018; 166 Hu (10.1016/j.envpol.2020.114496_bib31) 2016; 4 Naville (10.1016/j.envpol.2020.114496_bib48) 2013; 27 Chamorro-Garcia (10.1016/j.envpol.2020.114496_bib10) 2017; 8 Hacquard (10.1016/j.envpol.2020.114496_bib26) 2015; 17 Pfalzer (10.1016/j.envpol.2020.114496_bib54) 2016; 48 Fu (10.1016/j.envpol.2020.114496_bib20) 2015; 117 Hansen (10.1016/j.envpol.2020.114496_bib29) 2015; 7 Velagapudi (10.1016/j.envpol.2020.114496_bib68) 2010; 51 Koliada (10.1016/j.envpol.2020.114496_bib37) 2017; 17 Labaronne (10.1016/j.envpol.2020.114496_bib41) 2017; 45 García-Mayor (10.1016/j.envpol.2020.114496_bib21) 2012; 59 Yang (10.1016/j.envpol.2020.114496_bib70) 2015; 65 Dahan (10.1016/j.envpol.2020.114496_bib14) 2018; 9 Yaghjyan (10.1016/j.envpol.2020.114496_bib69) 2015; 39 Hao (10.1016/j.envpol.2020.114496_bib30) 2012; 32 Banerjee (10.1016/j.envpol.2020.114496_bib3) 2018; 16 Zhou (10.1016/j.envpol.2020.114496_bib72) 2018; 164 Norman (10.1016/j.envpol.2020.114496_bib50) 2007; 52 Catron (10.1016/j.envpol.2020.114496_bib9) 2018; 167 Hahn-Townsend (10.1016/j.envpol.2020.114496_bib27) 2016; 30 Langille (10.1016/j.envpol.2020.114496_bib42) 2013; 31 Feige (10.1016/j.envpol.2020.114496_bib17) 2010; 118 Backhed (10.1016/j.envpol.2020.114496_bib1) 2004 Kim (10.1016/j.envpol.2020.114496_bib35) 2016; 70 Kostic (10.1016/j.envpol.2020.114496_bib38) 2013; 27 Stecher (10.1016/j.envpol.2020.114496_bib63) 2012; 109 Berry (10.1016/j.envpol.2020.114496_bib73) 2014; 5 Martín (10.1016/j.envpol.2020.114496_bib46) 2016; 7 Goodman (10.1016/j.envpol.2020.114496_bib23) 2014; 44 Grün (10.1016/j.envpol.2020.114496_bib24) 2007; 8 Roeselers (10.1016/j.envpol.2020.114496_bib57) 2011; 5 Louis (10.1016/j.envpol.2020.114496_bib44) 2014; 12 Cox (10.1016/j.envpol.2020.114496_bib12) 2013; 17 Stienstra (10.1016/j.envpol.2020.114496_bib64) 2006; vol. 2007 Semova (10.1016/j.envpol.2020.114496_bib59) 2012; 12 Hunt (10.1016/j.envpol.2020.114496_bib32) 2017; 159 Reátegui (10.1016/j.envpol.2020.114496_bib56) 2019; 43 Camp (10.1016/j.envpol.2020.114496_bib6) 2009; 136 Lv (10.1016/j.envpol.2020.114496_bib45) 2016; 24 Tehrani (10.1016/j.envpol.2020.114496_bib66) 2012; 24 Eveillard (10.1016/j.envpol.2020.114496_bib16) 2009; 236 Stojanoska (10.1016/j.envpol.2020.114496_bib65) 2017; 55 Thayer (10.1016/j.envpol.2020.114496_bib67) 2012; 120 Desvergne (10.1016/j.envpol.2020.114496_bib15) 2009; 304 Janesick (10.1016/j.envpol.2020.114496_bib33) 2016; 214 Csardi (10.1016/j.envpol.2020.114496_bib13) 2006; 1695 Li (10.1016/j.envpol.2020.114496_bib43) 2018; 33 Seth (10.1016/j.envpol.2020.114496_bib60) 2013; 6 Sommer (10.1016/j.envpol.2020.114496_bib61) 2015; 16 Petersen (10.1016/j.envpol.2020.114496_bib53) 2014; 16 Zamakhchari (10.1016/j.envpol.2020.114496_bib71) 2011; 6 |
References_xml | – volume: 44 start-page: 151 year: 2014 end-page: 175 ident: bib23 article-title: Do phthalates act as obesogens in humans? A systematic review of the epidemiological literature publication-title: Crit. Rev. Toxicol. contributor: fullname: Mattison – volume: 109 start-page: 1269 year: 2012 end-page: 1274 ident: bib63 article-title: Gut inflammation can boost horizontal gene transfer between pathogenic and commensal enterobacteriaceae publication-title: Proc. Natl. Acad. Sci. Unit. States Am. contributor: fullname: Walker – volume: 1695 start-page: 1 year: 2006 end-page: 9 ident: bib13 article-title: The igraph software package for complex network research publication-title: InterJ., Complex Syst. contributor: fullname: Nepusz – volume: 159 start-page: 588 year: 2017 end-page: 594 ident: bib32 article-title: Maternal diethylhexyl phthalate exposure affects adiposity and insulin tolerance in offspring in a pcna-dependent manner publication-title: Environ. Res. contributor: fullname: Waltz – volume: 16 start-page: 1024 year: 2014 end-page: 1033 ident: bib53 article-title: Defining dysbiosis and its influence on host immunity and disease publication-title: Cell Microbiol. contributor: fullname: Round – year: 2004 ident: bib1 article-title: Gut microbiota as an environmental factor that regulates fat storage publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Gordon – volume: 236 start-page: 282 year: 2009 end-page: 292 ident: bib16 article-title: Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (dehp) adult exposure in the liver using a systems biology approach publication-title: Toxicol. Appl. Pharmacol. contributor: fullname: Guillou – volume: 27 start-page: 701 year: 2013 end-page: 718 ident: bib38 article-title: Exploring host–microbiota interactions in animal models and humans publication-title: Genes Dev. contributor: fullname: Garrett – volume: 16 start-page: 62 year: 2015 ident: bib61 article-title: Site-specific programming of the host epithelial transcriptome by the gut microbiota publication-title: Genome Biol. contributor: fullname: Bäckhed – volume: 8 start-page: 161 year: 2007 end-page: 171 ident: bib24 article-title: Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis publication-title: Rev. Endocr. Metab. Disord. contributor: fullname: Blumberg – volume: 16 start-page: 567 year: 2018 ident: bib3 article-title: Keystone taxa as drivers of microbiome structure and functioning publication-title: Nat. Rev. Microbiol. contributor: fullname: van der Heijden – volume: 32 start-page: 619 year: 2012 end-page: 629 ident: bib30 article-title: The endocrine disruptor mono-(2-ethylhexyl) phthalate promotes adipocyte differentiation and induces obesity in mice publication-title: Biosci. Rep. contributor: fullname: Ma – volume: 190 start-page: 375 year: 2018 end-page: 382 ident: bib55 article-title: Di (2-ethylhexyl) phthalate and diethyl phthalate disrupt lipid metabolism, reduce fecundity and shortens lifespan of caenorhabditis elegans publication-title: Chemosphere contributor: fullname: Jass – volume: 8 start-page: 185 year: 2002 end-page: 192 ident: bib2 article-title: Chemical toxins: a hypothesis to explain the global obesity epidemic publication-title: J. Alternative Compl. Med. contributor: fullname: Baillie-Hamilton – volume: 51 start-page: 1101 year: 2010 end-page: 1112 ident: bib68 article-title: The gut microbiota modulates host energy and lipid metabolism in mice publication-title: J. Lipid Res. contributor: fullname: Orešič – volume: 10 start-page: 21 year: 2010 ident: bib51 article-title: Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity publication-title: BMC Physiol. contributor: fullname: Tanaka – volume: 12 start-page: 661 year: 2014 ident: bib44 article-title: The gut microbiota, bacterial metabolites and colorectal cancer publication-title: Nat. Rev. Microbiol. contributor: fullname: Flint – volume: 166 start-page: 382 year: 2018 end-page: 393 ident: bib34 article-title: Insights into a possible mechanism underlying the connection of carbendazim-induced lipid metabolism disorder and gut microbiota dysbiosis in mice publication-title: Toxicol. Sci. contributor: fullname: Jin – volume: 7 start-page: 409 year: 2016 ident: bib46 article-title: Gnotobiotic rodents: an in vivo model for the study of microbe–microbe interactions publication-title: Front. Microbiol. contributor: fullname: Langella – volume: 48 start-page: 545 year: 2016 end-page: 553 ident: bib54 article-title: Interactions between the colonic transcriptome, metabolome, and microbiome in mouse models of obesity-induced intestinal cancer publication-title: Physiol. Genom. contributor: fullname: Crott – volume: 7 start-page: 33 year: 2015 ident: bib29 article-title: The gut microbiome in cardio-metabolic health publication-title: Genome Med. contributor: fullname: Pedersen – volume: 45 start-page: 83 year: 2017 end-page: 93 ident: bib41 article-title: Low-dose pollutant mixture triggers metabolic disturbances in female mice leading to common and specific features as compared to a high-fat diet publication-title: J. Nutr. Biochem. contributor: fullname: Le Magueresse-Battistoni – volume: 5 year: 2010 ident: bib7 article-title: Dehp impairs zebrafish reproduction by affecting critical factors in oogenesis publication-title: PloS One contributor: fullname: Maradonna – volume: 29 start-page: 949 year: 2016 end-page: 951 ident: bib11 article-title: Sex-specific effects of arsenic exposure on the trajectory and function of the gut microbiome publication-title: Chem. Res. Toxicol. contributor: fullname: Lu – volume: 304 start-page: 43 year: 2009 end-page: 48 ident: bib15 article-title: Ppar-mediated activity of phthalates: a link to the obesity epidemic? publication-title: Mol. Cell. Endocrinol. contributor: fullname: Casals-Casas – volume: 52 start-page: 235 year: 2007 end-page: 242 ident: bib50 article-title: Studies of uptake, elimination, and late effects in atlantic salmon (salmo salar) dietary exposed to di-2-ethylhexyl phthalate (dehp) during early life publication-title: Arch. Environ. Contam. Toxicol. contributor: fullname: Norrgren – volume: 17 start-page: 603 year: 2015 end-page: 616 ident: bib26 article-title: Microbiota and host nutrition across plant and animal kingdoms publication-title: Cell Host Microbe contributor: fullname: Ley – volume: 32 start-page: S53 year: 2008 ident: bib8 article-title: Interference of pollutants with ppars: endocrine disruption meets metabolism publication-title: Int. J. Obes. contributor: fullname: Desvergne – volume: 55 start-page: 666 year: 2017 end-page: 681 ident: bib65 article-title: The influence of phthalates and bisphenol a on the obesity development and glucose metabolism disorders publication-title: Endocrine contributor: fullname: Abenavoli – volume: 39 start-page: 994 year: 2015 ident: bib69 article-title: Associations of urinary phthalates with body mass index, waist circumference, and serum lipids among females: national health and nutrition examination survey 1999–2004 publication-title: Int. J. Obes. contributor: fullname: Chang – volume: 65 start-page: 1331 year: 2015 end-page: 1340 ident: bib70 article-title: Gut dysbiosis is linked to hypertensionnovelty and significance publication-title: Hypertension contributor: fullname: Zubcevic – volume: 6 year: 2011 ident: bib71 article-title: Identification of rothia bacteria as gluten-degrading natural colonizers of the upper gastro-intestinal tract publication-title: PloS One contributor: fullname: Helmerhorst – volume: 17 start-page: 883 year: 2013 end-page: 894 ident: bib12 article-title: Pathways in microbe-induced obesity publication-title: Cell Metabol. contributor: fullname: Blaser – volume: 136 start-page: 1989 year: 2009 end-page: 2002 ident: bib6 article-title: Patterns and scales in gastrointestinal microbial ecology publication-title: Gastroenterology contributor: fullname: Rawls – volume: 214 start-page: 559 year: 2016 end-page: 565 ident: bib33 article-title: Obesogens: an emerging threat to public health publication-title: Am. J. Obstet. Gynecol. contributor: fullname: Blumberg – volume: 64 start-page: 82 year: 2016 end-page: 92 ident: bib4 article-title: The zebrafish as a model to study intestinal inflammation publication-title: Dev. Comp. Immunol. contributor: fullname: Brugman – volume: 10 year: 2015 ident: bib36 article-title: Di-(2-ethylhexyl)-phthalate (dehp) causes impaired adipocyte function and alters serum metabolites publication-title: PloS One contributor: fullname: Stumvoll – volume: 164 start-page: 453 year: 2018 end-page: 464 ident: bib72 article-title: Aflatoxin b1 disrupts gut-microbial metabolisms of short-chain fatty acids, long-chain fatty acids, and bile acids in male f344 rats publication-title: Toxicol. Sci. contributor: fullname: Wang – volume: 33 start-page: 1220 year: 2018 end-page: 1226 ident: bib43 article-title: Involvement of shared mucosal-associated microbiota in the duodenum and rectum in diarrhea-predominant irritable bowel syndrome publication-title: J. Gastroenterol. Hepatol. contributor: fullname: Hou – volume: 24 start-page: 305 year: 2012 end-page: 311 ident: bib66 article-title: Obesity and its associated disease: a role for microbiota? publication-title: Neuro Gastroenterol. Motil. contributor: fullname: Srinivasan – volume: 31 start-page: 814 year: 2013 end-page: 821 ident: bib42 article-title: Predictive functional profiling of microbial communities using 16s rrna marker gene sequences publication-title: Nat. Biotechnol. contributor: fullname: Knight – volume: 9 year: 2018 ident: bib14 article-title: Exposure to arsenic alters the microbiome of larval zebrafish publication-title: Front. Microbiol. contributor: fullname: Perron – volume: 167 start-page: 468 year: 2018 end-page: 483 ident: bib9 article-title: Host developmental toxicity of bpa and bpa alternatives is inversely related to microbiota disruption in zebrafish publication-title: Toxicol. Sci. contributor: fullname: Gaballah – volume: 27 start-page: 3860 year: 2013 end-page: 3870 ident: bib48 article-title: Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice publication-title: Faseb. J. contributor: fullname: Bégeot – volume: 50 start-page: 2575 year: 2012 end-page: 2583 ident: bib18 article-title: Analysis of phthalates in food products and packaging materials sold on the belgian market publication-title: Food Chem. Toxicol. contributor: fullname: Vanermen – volume: 7 start-page: 189 year: 2016 end-page: 200 ident: bib47 article-title: Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism publication-title: Gut Microb. contributor: fullname: Preston – volume: 30 year: 2016 ident: bib27 article-title: Metabolic dysfunction induced by prenatal exposure to bisphenol-a and diethyl hexyl phthalate: exacerbation by high fat diet publication-title: Faseb. J. contributor: fullname: MohanKumar – volume: 159 start-page: 143 year: 2015 end-page: 153 ident: bib25 article-title: The gut microbiota and type 1 diabetes publication-title: Clin. Immunol. contributor: fullname: Wen – volume: 117 start-page: 817 year: 2015 end-page: 824 ident: bib20 article-title: The gut microbiome contributes to a substantial proportion of the variation in blood lipidsnovelty and significance publication-title: Circ. Res. contributor: fullname: Weersma – volume: 70 start-page: 466 year: 2016 end-page: 472 ident: bib35 article-title: Association of diethylhexyl phthalate with obesity-related markers and body mass change from birth to 3 months of age publication-title: J. Epidemiol. Community Health contributor: fullname: Kim – volume: 210 start-page: 21 year: 2007 end-page: 33 ident: bib19 article-title: Occurrence and daily variation of phthalate metabolites in the urine of an adult population publication-title: Int. J. Hyg Environ. Health contributor: fullname: Liebl – volume: 43 start-page: 52 year: 2019 ident: bib56 article-title: Cluster analysis of obesity disease based on comorbidities extracted from clinical notes publication-title: J. Med. Syst. contributor: fullname: Duque – volume: vol. 288 year: 2017 ident: bib28 publication-title: Prevalence of Obesity Among Adults and Youth: United states, 2015–2016 contributor: fullname: Ogden – volume: 115 start-page: 876 year: 2007 ident: bib62 article-title: Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult us males publication-title: Environ. Health Perspect. contributor: fullname: Swan – volume: 59 start-page: 261 year: 2012 end-page: 267 ident: bib21 article-title: Endocrine disruptors and obesity: Obesogens publication-title: Endocrinol. Nutr. contributor: fullname: Giménez – volume: 17 start-page: 120 year: 2017 ident: bib37 article-title: Association between body mass index and firmicutes/bacteroidetes ratio in an adult Ukrainian population publication-title: BMC Microbiol. contributor: fullname: Tkach – volume: 12 start-page: 277 year: 2012 end-page: 288 ident: bib59 article-title: Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish publication-title: Cell Host Microbe contributor: fullname: Rawls – volume: 120 start-page: 779 year: 2012 ident: bib67 article-title: Role of environmental chemicals in diabetes and obesity: a national toxicology program workshop review publication-title: Environ. Health Perspect. contributor: fullname: Gallo – volume: 4 start-page: 26 year: 2016 ident: bib31 article-title: Effect of postnatal low-dose exposure to environmental chemicals on the gut microbiome in a rodent model publication-title: Microbiome contributor: fullname: Teitelbaum – volume: 11 year: 2016 ident: bib22 article-title: Triclosan exposure is associated with rapid restructuring of the microbiome in adult zebrafish publication-title: PloS One contributor: fullname: Sharpton – volume: 27 start-page: 201 year: 2012 end-page: 214 ident: bib39 article-title: Effects of gut microbes on nutrient absorption and energy regulation publication-title: Nutr. Clin. Pract. contributor: fullname: DiBaise – volume: 27 start-page: 1E year: 2012 end-page: 5 ident: bib40 article-title: Using qiime to analyze 16s rrna gene sequences from microbial communities publication-title: Curr. Protocols Microbiol. contributor: fullname: Knight – volume: 245 start-page: 1086 year: 2019 end-page: 1094 ident: bib5 article-title: Examining the responses of the zebrafish (danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate publication-title: Environ. Pollut. contributor: fullname: Bisesi – volume: 38 start-page: 1250 year: 2003 end-page: 1257 ident: bib58 article-title: Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium publication-title: Hepatology contributor: fullname: Nantz – volume: 5 start-page: 1 year: 2014 end-page: 14 ident: bib73 article-title: Deciphering microbial interactions and detecting keystone species with co-occurrence networks publication-title: Front. Microbiol. contributor: fullname: Widder – volume: 5 start-page: 1595 year: 2011 end-page: 1608 ident: bib57 article-title: Evidence for a core gut microbiota in the zebrafish publication-title: ISME J. contributor: fullname: Rawls – volume: 8 start-page: 1 year: 2017 end-page: 13 ident: bib10 article-title: Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice publication-title: Nat. Commun. contributor: fullname: Blumberg – volume: 24 start-page: 368 year: 2016 end-page: 378 ident: bib45 article-title: Dehp induces obesity and hypothyroidism through both central and peripheral pathways in c3h/he mice publication-title: Obesity contributor: fullname: Ma – volume: 39 start-page: 84 year: 2014 end-page: 97 ident: bib49 article-title: The backbone of bipartite projections: inferring relationships from co-authorship, co-sponsorship, co-attendance and other co-behaviors publication-title: Soc. Network. contributor: fullname: Neal – volume: 118 start-page: 234 year: 2010 ident: bib17 article-title: The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific pparα-dependent mechanisms publication-title: Environ. Health Perspect. contributor: fullname: Gonzalez – volume: 6 start-page: 1080 year: 2013 end-page: 1088 ident: bib60 article-title: The emerging use of zebrafish to model metabolic disease publication-title: Disease Models Mech.s contributor: fullname: Barroso – volume: 30 start-page: 3123 year: 2014 end-page: 3124 ident: bib52 article-title: Stamp: Statistical analysis of taxonomic and functional profiles publication-title: Bioinformatics contributor: fullname: Beiko – volume: vol. 2007 year: 2006 ident: bib64 publication-title: Ppars, Obesity, and Inflammation contributor: fullname: Kersten – volume: 10 issue: 12 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib36 article-title: Di-(2-ethylhexyl)-phthalate (dehp) causes impaired adipocyte function and alters serum metabolites publication-title: PloS One doi: 10.1371/journal.pone.0143190 contributor: fullname: Klöting – volume: 55 start-page: 666 issue: 3 year: 2017 ident: 10.1016/j.envpol.2020.114496_bib65 article-title: The influence of phthalates and bisphenol a on the obesity development and glucose metabolism disorders publication-title: Endocrine doi: 10.1007/s12020-016-1158-4 contributor: fullname: Stojanoska – volume: 120 start-page: 779 issue: 6 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib67 article-title: Role of environmental chemicals in diabetes and obesity: a national toxicology program workshop review publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1104597 contributor: fullname: Thayer – volume: 304 start-page: 43 issue: 1 year: 2009 ident: 10.1016/j.envpol.2020.114496_bib15 article-title: Ppar-mediated activity of phthalates: a link to the obesity epidemic? publication-title: Mol. Cell. Endocrinol. doi: 10.1016/j.mce.2009.02.017 contributor: fullname: Desvergne – volume: 50 start-page: 2575 issue: 7 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib18 article-title: Analysis of phthalates in food products and packaging materials sold on the belgian market publication-title: Food Chem. Toxicol. doi: 10.1016/j.fct.2012.04.029 contributor: fullname: Fierens – volume: 210 start-page: 21 issue: 1 year: 2007 ident: 10.1016/j.envpol.2020.114496_bib19 article-title: Occurrence and daily variation of phthalate metabolites in the urine of an adult population publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2006.09.005 contributor: fullname: Fromme – volume: 4 start-page: 26 issue: 1 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib31 article-title: Effect of postnatal low-dose exposure to environmental chemicals on the gut microbiome in a rodent model publication-title: Microbiome doi: 10.1186/s40168-016-0173-2 contributor: fullname: Hu – volume: 16 start-page: 62 issue: 1 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib61 article-title: Site-specific programming of the host epithelial transcriptome by the gut microbiota publication-title: Genome Biol. doi: 10.1186/s13059-015-0614-4 contributor: fullname: Sommer – volume: 109 start-page: 1269 issue: 4 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib63 article-title: Gut inflammation can boost horizontal gene transfer between pathogenic and commensal enterobacteriaceae publication-title: Proc. Natl. Acad. Sci. Unit. States Am. doi: 10.1073/pnas.1113246109 contributor: fullname: Stecher – volume: 117 start-page: 817 issue: 9 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib20 article-title: The gut microbiome contributes to a substantial proportion of the variation in blood lipidsnovelty and significance publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.115.306807 contributor: fullname: Fu – volume: 159 start-page: 143 issue: 2 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib25 article-title: The gut microbiota and type 1 diabetes publication-title: Clin. Immunol. doi: 10.1016/j.clim.2015.05.013 contributor: fullname: Gülden – volume: 5 start-page: 1 year: 2014 ident: 10.1016/j.envpol.2020.114496_bib73 article-title: Deciphering microbial interactions and detecting keystone species with co-occurrence networks publication-title: Front. Microbiol. doi: 10.3389/fmicb.2014.00219 contributor: fullname: Berry – volume: 6 issue: 9 year: 2011 ident: 10.1016/j.envpol.2020.114496_bib71 article-title: Identification of rothia bacteria as gluten-degrading natural colonizers of the upper gastro-intestinal tract publication-title: PloS One doi: 10.1371/journal.pone.0024455 contributor: fullname: Zamakhchari – volume: 214 start-page: 559 issue: 5 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib33 article-title: Obesogens: an emerging threat to public health publication-title: Am. J. Obstet. Gynecol. doi: 10.1016/j.ajog.2016.01.182 contributor: fullname: Janesick – volume: 27 start-page: 201 issue: 2 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib39 article-title: Effects of gut microbes on nutrient absorption and energy regulation publication-title: Nutr. Clin. Pract. doi: 10.1177/0884533611436116 contributor: fullname: Krajmalnik-Brown – volume: 236 start-page: 282 issue: 3 year: 2009 ident: 10.1016/j.envpol.2020.114496_bib16 article-title: Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (dehp) adult exposure in the liver using a systems biology approach publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2009.02.008 contributor: fullname: Eveillard – volume: 24 start-page: 368 issue: 2 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib45 article-title: Dehp induces obesity and hypothyroidism through both central and peripheral pathways in c3h/he mice publication-title: Obesity doi: 10.1002/oby.21359 contributor: fullname: Lv – volume: 167 start-page: 468 issue: 2 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib9 article-title: Host developmental toxicity of bpa and bpa alternatives is inversely related to microbiota disruption in zebrafish publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kfy261 contributor: fullname: Catron – volume: 5 issue: 4 year: 2010 ident: 10.1016/j.envpol.2020.114496_bib7 article-title: Dehp impairs zebrafish reproduction by affecting critical factors in oogenesis publication-title: PloS One doi: 10.1371/journal.pone.0010201 contributor: fullname: Carnevali – volume: 166 start-page: 382 issue: 2 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib34 article-title: Insights into a possible mechanism underlying the connection of carbendazim-induced lipid metabolism disorder and gut microbiota dysbiosis in mice publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kfy205 contributor: fullname: Jin – year: 2004 ident: 10.1016/j.envpol.2020.114496_bib1 article-title: Gut microbiota as an environmental factor that regulates fat storage contributor: fullname: Backhed – volume: 17 start-page: 883 issue: 6 year: 2013 ident: 10.1016/j.envpol.2020.114496_bib12 article-title: Pathways in microbe-induced obesity publication-title: Cell Metabol. doi: 10.1016/j.cmet.2013.05.004 contributor: fullname: Cox – volume: 8 start-page: 161 issue: 2 year: 2007 ident: 10.1016/j.envpol.2020.114496_bib24 article-title: Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis publication-title: Rev. Endocr. Metab. Disord. doi: 10.1007/s11154-007-9049-x contributor: fullname: Grün – volume: vol. 288 year: 2017 ident: 10.1016/j.envpol.2020.114496_bib28 contributor: fullname: Hales – volume: 51 start-page: 1101 issue: 5 year: 2010 ident: 10.1016/j.envpol.2020.114496_bib68 article-title: The gut microbiota modulates host energy and lipid metabolism in mice publication-title: J. Lipid Res. doi: 10.1194/jlr.M002774 contributor: fullname: Velagapudi – volume: 59 start-page: 261 issue: 4 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib21 article-title: Endocrine disruptors and obesity: Obesogens publication-title: Endocrinol. Nutr. doi: 10.1016/j.endonu.2011.11.008 contributor: fullname: García-Mayor – volume: 31 start-page: 814 issue: 9 year: 2013 ident: 10.1016/j.envpol.2020.114496_bib42 article-title: Predictive functional profiling of microbial communities using 16s rrna marker gene sequences publication-title: Nat. Biotechnol. doi: 10.1038/nbt.2676 contributor: fullname: Langille – volume: 27 start-page: 3860 issue: 9 year: 2013 ident: 10.1016/j.envpol.2020.114496_bib48 article-title: Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice publication-title: Faseb. J. doi: 10.1096/fj.13-231670 contributor: fullname: Naville – volume: 32 start-page: S53 issue: S6 year: 2008 ident: 10.1016/j.envpol.2020.114496_bib8 article-title: Interference of pollutants with ppars: endocrine disruption meets metabolism publication-title: Int. J. Obes. doi: 10.1038/ijo.2008.207 contributor: fullname: Casals-Casas – volume: 27 start-page: 701 issue: 7 year: 2013 ident: 10.1016/j.envpol.2020.114496_bib38 article-title: Exploring host–microbiota interactions in animal models and humans publication-title: Genes Dev. doi: 10.1101/gad.212522.112 contributor: fullname: Kostic – volume: 38 start-page: 1250 issue: 5 year: 2003 ident: 10.1016/j.envpol.2020.114496_bib58 article-title: Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium publication-title: Hepatology doi: 10.1053/jhep.2003.50446 contributor: fullname: Selmi – volume: 32 start-page: 619 issue: 6 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib30 article-title: The endocrine disruptor mono-(2-ethylhexyl) phthalate promotes adipocyte differentiation and induces obesity in mice publication-title: Biosci. Rep. doi: 10.1042/BSR20120042 contributor: fullname: Hao – volume: 5 start-page: 1595 issue: 10 year: 2011 ident: 10.1016/j.envpol.2020.114496_bib57 article-title: Evidence for a core gut microbiota in the zebrafish publication-title: ISME J. doi: 10.1038/ismej.2011.38 contributor: fullname: Roeselers – volume: 1695 start-page: 1 issue: 5 year: 2006 ident: 10.1016/j.envpol.2020.114496_bib13 article-title: The igraph software package for complex network research publication-title: InterJ., Complex Syst. contributor: fullname: Csardi – volume: 11 issue: 5 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib22 article-title: Triclosan exposure is associated with rapid restructuring of the microbiome in adult zebrafish publication-title: PloS One doi: 10.1371/journal.pone.0154632 contributor: fullname: Gaulke – volume: 7 start-page: 189 issue: 3 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib47 article-title: Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism publication-title: Gut Microb. doi: 10.1080/19490976.2015.1134082 contributor: fullname: Morrison – volume: 64 start-page: 82 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib4 article-title: The zebrafish as a model to study intestinal inflammation publication-title: Dev. Comp. Immunol. doi: 10.1016/j.dci.2016.02.020 contributor: fullname: Brugman – volume: 17 start-page: 603 issue: 5 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib26 article-title: Microbiota and host nutrition across plant and animal kingdoms publication-title: Cell Host Microbe doi: 10.1016/j.chom.2015.04.009 contributor: fullname: Hacquard – volume: vol. 2007 year: 2006 ident: 10.1016/j.envpol.2020.114496_bib64 contributor: fullname: Stienstra – volume: 48 start-page: 545 issue: 8 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib54 article-title: Interactions between the colonic transcriptome, metabolome, and microbiome in mouse models of obesity-induced intestinal cancer publication-title: Physiol. Genom. doi: 10.1152/physiolgenomics.00034.2016 contributor: fullname: Pfalzer – volume: 52 start-page: 235 issue: 2 year: 2007 ident: 10.1016/j.envpol.2020.114496_bib50 article-title: Studies of uptake, elimination, and late effects in atlantic salmon (salmo salar) dietary exposed to di-2-ethylhexyl phthalate (dehp) during early life publication-title: Arch. Environ. Contam. Toxicol. doi: 10.1007/s00244-005-5089-y contributor: fullname: Norman – volume: 9 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib14 article-title: Exposure to arsenic alters the microbiome of larval zebrafish publication-title: Front. Microbiol. doi: 10.3389/fmicb.2018.01323 contributor: fullname: Dahan – volume: 115 start-page: 876 issue: 6 year: 2007 ident: 10.1016/j.envpol.2020.114496_bib62 article-title: Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult us males publication-title: Environ. Health Perspect. doi: 10.1289/ehp.9882 contributor: fullname: Stahlhut – volume: 6 start-page: 1080 issue: 5 year: 2013 ident: 10.1016/j.envpol.2020.114496_bib60 article-title: The emerging use of zebrafish to model metabolic disease publication-title: Disease Models Mech.s doi: 10.1242/dmm.011346 contributor: fullname: Seth – volume: 12 start-page: 277 issue: 3 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib59 article-title: Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish publication-title: Cell Host Microbe doi: 10.1016/j.chom.2012.08.003 contributor: fullname: Semova – volume: 45 start-page: 83 year: 2017 ident: 10.1016/j.envpol.2020.114496_bib41 article-title: Low-dose pollutant mixture triggers metabolic disturbances in female mice leading to common and specific features as compared to a high-fat diet publication-title: J. Nutr. Biochem. doi: 10.1016/j.jnutbio.2017.04.001 contributor: fullname: Labaronne – volume: 7 start-page: 33 issue: 1 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib29 article-title: The gut microbiome in cardio-metabolic health publication-title: Genome Med. doi: 10.1186/s13073-015-0157-z contributor: fullname: Hansen – volume: 7 start-page: 409 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib46 article-title: Gnotobiotic rodents: an in vivo model for the study of microbe–microbe interactions publication-title: Front. Microbiol. doi: 10.3389/fmicb.2016.00409 contributor: fullname: Martín – volume: 27 start-page: 1E issue: 1 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib40 article-title: Using qiime to analyze 16s rrna gene sequences from microbial communities publication-title: Curr. Protocols Microbiol. doi: 10.1002/9780471729259.mc01e05s27 contributor: fullname: Kuczynski – volume: 65 start-page: 1331 issue: 6 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib70 article-title: Gut dysbiosis is linked to hypertensionnovelty and significance publication-title: Hypertension doi: 10.1161/HYPERTENSIONAHA.115.05315 contributor: fullname: Yang – volume: 16 start-page: 567 issue: 9 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib3 article-title: Keystone taxa as drivers of microbiome structure and functioning publication-title: Nat. Rev. Microbiol. doi: 10.1038/s41579-018-0024-1 contributor: fullname: Banerjee – volume: 39 start-page: 84 year: 2014 ident: 10.1016/j.envpol.2020.114496_bib49 article-title: The backbone of bipartite projections: inferring relationships from co-authorship, co-sponsorship, co-attendance and other co-behaviors publication-title: Soc. Network. doi: 10.1016/j.socnet.2014.06.001 contributor: fullname: Neal – volume: 8 start-page: 185 issue: 2 year: 2002 ident: 10.1016/j.envpol.2020.114496_bib2 article-title: Chemical toxins: a hypothesis to explain the global obesity epidemic publication-title: J. Alternative Compl. Med. doi: 10.1089/107555302317371479 contributor: fullname: Baillie-Hamilton – volume: 43 start-page: 52 issue: 3 year: 2019 ident: 10.1016/j.envpol.2020.114496_bib56 article-title: Cluster analysis of obesity disease based on comorbidities extracted from clinical notes publication-title: J. Med. Syst. doi: 10.1007/s10916-019-1172-1 contributor: fullname: Reátegui – volume: 245 start-page: 1086 year: 2019 ident: 10.1016/j.envpol.2020.114496_bib5 article-title: Examining the responses of the zebrafish (danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate publication-title: Environ. Pollut. doi: 10.1016/j.envpol.2018.11.032 contributor: fullname: Buerger – volume: 10 start-page: 21 issue: 1 year: 2010 ident: 10.1016/j.envpol.2020.114496_bib51 article-title: Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity publication-title: BMC Physiol. doi: 10.1186/1472-6793-10-21 contributor: fullname: Oka – volume: 118 start-page: 234 issue: 2 year: 2010 ident: 10.1016/j.envpol.2020.114496_bib17 article-title: The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific pparα-dependent mechanisms publication-title: Environ. Health Perspect. doi: 10.1289/ehp.0901217 contributor: fullname: Feige – volume: 17 start-page: 120 issue: 1 year: 2017 ident: 10.1016/j.envpol.2020.114496_bib37 article-title: Association between body mass index and firmicutes/bacteroidetes ratio in an adult Ukrainian population publication-title: BMC Microbiol. doi: 10.1186/s12866-017-1027-1 contributor: fullname: Koliada – volume: 16 start-page: 1024 issue: 7 year: 2014 ident: 10.1016/j.envpol.2020.114496_bib53 article-title: Defining dysbiosis and its influence on host immunity and disease publication-title: Cell Microbiol. doi: 10.1111/cmi.12308 contributor: fullname: Petersen – volume: 29 start-page: 949 issue: 6 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib11 article-title: Sex-specific effects of arsenic exposure on the trajectory and function of the gut microbiome publication-title: Chem. Res. Toxicol. doi: 10.1021/acs.chemrestox.6b00066 contributor: fullname: Chi – volume: 190 start-page: 375 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib55 article-title: Di (2-ethylhexyl) phthalate and diethyl phthalate disrupt lipid metabolism, reduce fecundity and shortens lifespan of caenorhabditis elegans publication-title: Chemosphere doi: 10.1016/j.chemosphere.2017.09.123 contributor: fullname: Pradhan – volume: 12 start-page: 661 issue: 10 year: 2014 ident: 10.1016/j.envpol.2020.114496_bib44 article-title: The gut microbiota, bacterial metabolites and colorectal cancer publication-title: Nat. Rev. Microbiol. doi: 10.1038/nrmicro3344 contributor: fullname: Louis – volume: 70 start-page: 466 issue: 5 year: 2016 ident: 10.1016/j.envpol.2020.114496_bib35 article-title: Association of diethylhexyl phthalate with obesity-related markers and body mass change from birth to 3 months of age publication-title: J. Epidemiol. Community Health doi: 10.1136/jech-2015-206315 contributor: fullname: Kim – volume: 30 start-page: 3123 issue: 21 year: 2014 ident: 10.1016/j.envpol.2020.114496_bib52 article-title: Stamp: Statistical analysis of taxonomic and functional profiles publication-title: Bioinformatics doi: 10.1093/bioinformatics/btu494 contributor: fullname: Parks – volume: 24 start-page: 305 issue: 4 year: 2012 ident: 10.1016/j.envpol.2020.114496_bib66 article-title: Obesity and its associated disease: a role for microbiota? publication-title: Neuro Gastroenterol. Motil. doi: 10.1111/j.1365-2982.2012.01895.x contributor: fullname: Tehrani – volume: 159 start-page: 588 year: 2017 ident: 10.1016/j.envpol.2020.114496_bib32 article-title: Maternal diethylhexyl phthalate exposure affects adiposity and insulin tolerance in offspring in a pcna-dependent manner publication-title: Environ. Res. doi: 10.1016/j.envres.2017.09.004 contributor: fullname: Hunt – volume: 39 start-page: 994 issue: 6 year: 2015 ident: 10.1016/j.envpol.2020.114496_bib69 article-title: Associations of urinary phthalates with body mass index, waist circumference, and serum lipids among females: national health and nutrition examination survey 1999–2004 publication-title: Int. J. Obes. doi: 10.1038/ijo.2015.8 contributor: fullname: Yaghjyan – volume: 44 start-page: 151 issue: 2 year: 2014 ident: 10.1016/j.envpol.2020.114496_bib23 article-title: Do phthalates act as obesogens in humans? A systematic review of the epidemiological literature publication-title: Crit. Rev. Toxicol. doi: 10.3109/10408444.2013.860076 contributor: fullname: Goodman – volume: 8 start-page: 1 issue: 1 year: 2017 ident: 10.1016/j.envpol.2020.114496_bib10 article-title: Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice publication-title: Nat. Commun. doi: 10.1038/s41467-017-01944-z contributor: fullname: Chamorro-Garcia – volume: 33 start-page: 1220 issue: 6 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib43 article-title: Involvement of shared mucosal-associated microbiota in the duodenum and rectum in diarrhea-predominant irritable bowel syndrome publication-title: J. Gastroenterol. Hepatol. doi: 10.1111/jgh.14059 contributor: fullname: Li – volume: 136 start-page: 1989 issue: 6 year: 2009 ident: 10.1016/j.envpol.2020.114496_bib6 article-title: Patterns and scales in gastrointestinal microbial ecology publication-title: Gastroenterology doi: 10.1053/j.gastro.2009.02.075 contributor: fullname: Camp – volume: 30 issue: 1_Suppl. ment year: 2016 ident: 10.1016/j.envpol.2020.114496_bib27 article-title: Metabolic dysfunction induced by prenatal exposure to bisphenol-a and diethyl hexyl phthalate: exacerbation by high fat diet publication-title: Faseb. J. contributor: fullname: Hahn-Townsend – volume: 164 start-page: 453 issue: 2 year: 2018 ident: 10.1016/j.envpol.2020.114496_bib72 article-title: Aflatoxin b1 disrupts gut-microbial metabolisms of short-chain fatty acids, long-chain fatty acids, and bile acids in male f344 rats publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kfy102 contributor: fullname: Zhou |
SSID | ssj0004333 |
Score | 2.5162792 |
Snippet | Microbiome community structure is intimately involved in key biological functions in the gastrointestinal (GI) system including nutrient absorption and lipid... |
SourceID | proquest crossref elsevier |
SourceType | Aggregation Database Publisher |
StartPage | 114496 |
SubjectTerms | Gastrointestinal system Microbiome Network analysis Obesity Phthalates Zebrafish |
Title | Gastrointestinal dysbiosis following diethylhexyl phthalate exposure in zebrafish (Danio rerio): Altered microbial diversity, functionality, and network connectivity |
URI | https://dx.doi.org/10.1016/j.envpol.2020.114496 https://search.proquest.com/docview/2435187716 |
Volume | 265 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELaqcoEDgi0V5VEZCSGQCLtrOw9zW1UtC0i9QKXeIjt2tKm2drRJocuBf8P_ZMZOVEBISBwT-RFl7JnPnm9mCHnOjZVa6lmSz6VKhM6KpNAqT0SVyhTgw6ywgSB7mi3PxIfz9HyHHI2xMEirHHR_1OlBWw9vpsPfnLZNM_0EpwcAw7BZJRdpzjGiXKQzrGLw5vsNzUPwWE4eGifYegyfCxwv6760Hh0QLCTNFZi6_-_m6Q9FHazPyT1yd4CNdBG_7D7ZsW5C9hYOjsyXW_qCBiJnuCGfkDu_5BickP3jm1A2GGHYy90e-fFOdf3GY74I2OY4utl2uvFd09EaVof_Cv2paSyIcr2y19s1bVf9Sq0BnVJ73Xq8W6SNo9_Q91w33Yq-xIB1TzcwtX_1li7QE28NvWxCtiecYWSBvKZoUOM9ZHhUzlAXKem0QvJNFctaPCBnJ8efj5bJULQhqTiXfVJIZQASZZjKrcoNFpk1tjYznoPdqzVnNiu0NsIynjNmQGNgUSyVMsUxmVrN98mu884-JNQWnM-rumY14yKvpC4koDHBhKozZgU_IMkoq7KNuTnKkbR2UUbZlijbMsr2gOSjQMvf1lgJ5uMfPZ-N8i9h-6FPRTnrr7qSAdycFzmcOh_99-iPyW18ihTBJ2S331zZpwB1en0Y1vIhubV4_3F5-hNRcAK_ |
link.rule.ids | 314,780,784,4502,24116,27924,27925,45585,45679 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELZKOQCHCrZUlPIwEkIgke6u7cQJt1XVskDphVbqzbJjRxu0TaJNCl0O_Bv-JzN2ogJCQuKYxHaizOuz_XmGkOfcusxkZhLJaaYjYZI0So2WkcjjLAb4MEmdJ8ieJPMz8f48Pt8gB8NZGKRV9r4_-HTvrfs74_5vjpuyHH-C2QOAYTDWjItYcnmD3BQxoF9Q6v3v1zwPwUM9eWgdYfPh_JwnebnqS1PjDgTzWXMF5u7_e3z6w1P78HN0l2z1uJHOwqfdIxuuGpHtWQVz5os1fUE9k9MvkY_InV-SDI7IzuH1WTYYoTfmdpv8eKvbblVjwgiwcxzdrltT1m3Z0gLUo_4K_aktHchyuXBX6yVtFt1CLwGeUnfV1Li4SMuKfsPN56JsF_Qlnliv6QpeXb96Q2e4Fe8svSh9uid8w0ADeU0xooaFSH-pK0urwEmnObJv8lDX4j45Ozo8PZhHfdWGKOc866I00xYwUYK53HJpscqsdYWdcAmBrzCcuSQ1xgrHuGTMgsvAqlg6ZppjNrWC75DNqq7cA0Jdyvk0LwpWMC5knpk0AzgmmNBFwpzguyQaZKWakJxDDay1zyrIVqFsVZDtLpGDQNVvSqYgfvyj57NB_grsDzdVdOXqy1YxwJvTVMK08-F_j_6U3JqffjxWx-9OPuyR2_gk8AUfkc1udekeA-7pzBOv1z8BUMIEXA |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Gastrointestinal+dysbiosis+following+diethylhexyl+phthalate+exposure+in+zebrafish+%28Danio+rerio%29%3A+Altered+microbial+diversity%2C+functionality%2C+and+network+connectivity&rft.jtitle=Environmental+pollution+%281987%29&rft.au=Buerger%2C+Amanda+N.&rft.au=Dillon%2C+David+T.&rft.au=Schmidt%2C+Jordan&rft.au=Yang%2C+Tao&rft.date=2020-10-01&rft.issn=0269-7491&rft.volume=265&rft.spage=114496&rft_id=info:doi/10.1016%2Fj.envpol.2020.114496&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_envpol_2020_114496 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0269-7491&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0269-7491&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0269-7491&client=summon |