Manganese, selenium and other trace elements in spinal cord, liver and bone in motor neurone disease

• Published in: European neurology Vol. 31; no. 1; p. 7
• Main Authors: Mitchell, J D, East, B W, Harris, I A, Pentland, B
• Format: Journal Article
• Language: English
• Published: Switzerland 1991
• Subjects: Adult; Aged; Aged, 80 and over; Bone and Bones - chemistry; Female; Humans; Liver - chemistry; Male; Manganese - analysis; Middle Aged; Motor Neurons; Neuromuscular Diseases - metabolism; Neutron Activation Analysis; Selenium - analysis; Spinal Cord - chemistry; Trace Elements - analysis

Trace element levels were measured by neutron activation analysis in spinal cord, liver and bone of 7 control patients dying of non-neurological disease and 15 patients dying of motor neurone disease (MND). The concentration of selenium was significantly elevated in the cervical cord, liver and bone...