Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies

• Published in: Bioorganic chemistry Vol. 93; p. 103313
• Main Authors: Mamedova, Gulnar, Mahmudova, Adila, Mamedov, Sabir, Erden, Yavuz, Taslimi, Parham, Tüzün, Burak, Tas, Recep, Farzaliyev, Vagif, Sujayev, Afsun, Alwasel, Saleh H., Gulçin, İlhami
• Format: Journal Article
• Language: English
• Published: SAN DIEGO Elsevier Inc 01.12.2019; Elsevier
• Subjects: Anticancer; Biochemistry & Molecular Biology; Chemistry; Chemistry, Organic; Cholinesterase; Enzyme inhibition; Life Sciences & Biomedicine; Molecular docking; Physical Sciences; Pyrazole; Science & Technology; Sulfamide; Sulfamide; Enzyme inhibition; Anticancer; Pyrazole; Molecular docking; Cholinesterase; BUTYRYLCHOLINESTERASE; CRYSTAL-STRUCTURE; ALPHA-GLYCOSIDASE; POTENT; ACETYLCHOLINESTERASE; ANTIOXIDANT; CARBONIC-ANHYDRASE INHIBITION; BIOLOGICAL EVALUATION; DERIVATIVES; POLYPHENOL CONTENTS

[Display omitted] •A serie of novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines was synthesised.•These precursors have been characterized by 1H and 13C NMR and FTIR spectroscopies.•Molecular docking studies of these compounds were studied.•Their inhibition effects on A...