Identification of Differentially Expressed Proteins in Serum of Obese Patients by Isobaric Tags for Relative and Absolute Quantification (iTRAQ)-Coupled 2D LC-MS

• Published in: Medical science monitor Vol. 26; pp. e924882 - e924882-7
• Main Authors: Zhang, Ying, Chen, Zhong, He, Yue, Wang, Jianxia, Jiang, Minhui, Xu, Jianjuan, Chen, Minghua, Feng, Yaling
• Format: Journal Article
• Language: English
• Published: United States International Scientific Literature, Inc 02.08.2020
• Subjects: Adult; Blood Proteins - classification; Blood Proteins - genetics; Blood Proteins - metabolism; Body Mass Index; Case-Control Studies; Chromatography, Liquid; Clinical Research; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Humans; Male; Metabolic Networks and Pathways - genetics; Molecular Sequence Annotation; Obesity, Abdominal - blood; Obesity, Abdominal - genetics; Obesity, Abdominal - pathology; Staining and Labeling - methods; Tandem Mass Spectrometry

BACKGROUND The aim of this study was to identify the differentially expressed proteins of obese patients compared with normal participants and to provide a potential target for future investigation of obesity. MATERIAL AND METHODS We enrolled 10 obese male adults and 10 matched normal subjects. Seru...