Effect of oral protease inhibitor administration of gallbladder motility in patients with mild chronic pancreatitis

• Published in: Journal of gastroenterology Vol. 32; no. 3; pp. 374 - 379
• Main Authors: Sugiyama, Masanori, Atomi, Yutaka, Wada, Nobuaki, Kuroda, Akira, Muto, Tetsuichiro
• Format: Journal Article
• Language: English
• Published: Japan Springer Nature B.V 01.06.1997
• Subjects: Administration, Oral; Adult; Aged; Cholecystokinin; Cholecystokinin - blood; Cholecystokinin - drug effects; Chronic Disease; chronic pancreatitis; Contractility; Fasting; Female; Gabexate - analogs & derivatives; Gallbladder; Gallbladder - drug effects; Gallbladder - physiopathology; gallbladder motility; Guanidines - administration & dosage; Guanidines - pharmacology; Humans; Male; Middle Aged; Motility; Oral administration; Pancreatitis; Pancreatitis - blood; Pancreatitis - drug therapy; Pancreatitis - physiopathology; plasma cholecystokinin concentration; protease inhibitor; Protease Inhibitors - administration & dosage; Protease Inhibitors - pharmacology; Proteinase inhibitors; Radioimmunoassay; Yolk

Oral administration of a protease inhibitor (camostat) induces pancreatic hypersecretion via hormonal and neural systems in humans. Camostat may also affect gallbladder motility via these systems. The aim of this study was to evaluate the effect of camostat on gallbladder function. Gallbladder empty...