Nuezhenide of the fruits of Nuzhenzi (Ligustrum lucidum Ait.) is a functional analog of ghrelin - Wang, Chia-Hao; Tseng, Ching-Yu; Hsu, Wei-Li; Tzen, Jason T.C. (Journal of ethnopharmacology, 2025)
Keywords: agonists; calcium; cell lines; cell proliferation; Cell Survival - drug effects; cell viability; dried fruit; ERK1/2; Fruit; Ghrelin; ghrelin receptors; Growth hormone secretagogue receptor; HEK293 Cells; Humans; Ligustrum - chemistry; Ligustrum lucidum; Ligustrum lucidum Ait; MAP Kinase Signaling System - drug effects; memory; Mitogen-Activated Protein Kinase 1 - metabolism; Mitogen-Activated Protein Kinase 3 - metabolism; Molecular Docking Simulation; neuroprotective effect; Nuezhenide; Oriental traditional medicine; phospholipase C; phospholipases; phosphorylation; Phosphorylation - drug effects; Plant Extracts - chemistry; Plant Extracts - pharmacology; Receptors, Ghrelin - metabolism; therapeutics; Type C Phospholipases - metabolism; water solubility; Ligustrum lucidum Ait; ERK1/2; Growth hormone secretagogue receptor; Nuezhenide