Reduction of Milk Protein Antigenicity by Enzymatic Hydrolysis and Fermentation. A Review
Cow milk proteins are among the major food allergens. Reducing their antigenicity through enzymatic hydrolysis and microbial fermentation has received much attention. Both treatments are based on proteolysis of milk protein and deactivation of their IgE binding epitopes. Reduction of antigenicity is...
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Published in | Food reviews international Vol. 37; no. 3; pp. 276 - 295 |
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Main Authors | , |
Format | Journal Article |
Language | English |
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Taylor & Francis
03.04.2021
Taylor & Francis Ltd |
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Abstract | Cow milk proteins are among the major food allergens. Reducing their antigenicity through enzymatic hydrolysis and microbial fermentation has received much attention. Both treatments are based on proteolysis of milk protein and deactivation of their IgE binding epitopes. Reduction of antigenicity is mainly controlled by the source and specificity of the enzyme used and the reaction conditions. The whole proteolytic system of the enzyme used is involved in protein hydrolysis and strains of lactic acid bacteria exhibit variable reductions on milk proteins antigenicity. Both treatments can be considered as promising strategies to manage cow milk allergy. |
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AbstractList | Cow milk proteins are among the major food allergens. Reducing their antigenicity through enzymatic hydrolysis and microbial fermentation has received much attention. Both treatments are based on proteolysis of milk protein and deactivation of their IgE binding epitopes. Reduction of antigenicity is mainly controlled by the source and specificity of the enzyme used and the reaction conditions. The whole proteolytic system of the enzyme used is involved in protein hydrolysis and strains of lactic acid bacteria exhibit variable reductions on milk proteins antigenicity. Both treatments can be considered as promising strategies to manage cow milk allergy. |
Author | Abd El-Salam, Mohamed H. El-Shibiny, Safinaz |
Author_xml | – sequence: 1 givenname: Mohamed H. surname: Abd El-Salam fullname: Abd El-Salam, Mohamed H. email: mo_salam38@yahoo.com organization: National Research Centre – sequence: 2 givenname: Safinaz surname: El-Shibiny fullname: El-Shibiny, Safinaz organization: National Research Centre |
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SubjectTerms | Allergens Allergies Allergy Antigenicity Bacteria Cow's milk Deactivation Enzymes Epitopes Fermentation Food allergies Hydrolysis Immunoglobulin E Lactic acid Lactic acid bacteria Microorganisms Milk milk proteins Proteins Proteolysis Reduction Vegetable oils |
Title | Reduction of Milk Protein Antigenicity by Enzymatic Hydrolysis and Fermentation. A Review |
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