Relationship between HMGB1 content and MHC-II expression in circulating monocytes and spleen of mice challenged with zymosan

• Published in: Chinese journal of traumatology Vol. 12; no. 6; pp. 339 - 343
• Main Author: 吕艺 陆江阳 赵敏 李志宏 杨毅
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.12.2009; Burn Insitute,First Affiliated Hospital of PLA General Hospital,Beijing 100048,China%Department of Pathology,First Affiliated Hospital of PLA General Hospital,Beijing 100048,China
• Subjects: Animals; Histocompatibility Antigens Class II - analysis; HMGB1 Protein - analysis; Major histocompatibility complex; Male; MHC; Mice; Mice, Inbred C57BL; Monocytes; Monocytes - immunology; Multiple Organ Failure - immunology; Spleen; Spleen - immunology; Zymosan; Zymosan - pharmacology; 单核细胞; 迁移率; 酵母多糖; Zymosan; Spleen; Monocytes; Major histocompatibility complex; Major histocampatibility complex

Objective： To observe the regularity of change in high mobility group protein box 1 （HMGB 1） content in serum and spleen of mice with multiple organ dysfunction syndrome （MODS）, to analyze the correlation between HMGB 1 content and major histocompatibility complex （MHC）-II-I-Ab expression on monocyt...