Multi-step Flow Synthesis of the Anthelmintic Drug Praziquantel

• Published in: SynOpen (2017) Vol. 7; no. 3; pp. 362 - 370
• Main Authors: Phull, Manjinder Singh, Jadav, Surender Singh, Bohara, Chander Singh, Gundla, Rambabu, Mainkar, Prathama S
• Format: Journal Article
• Language: English
• Published: Georg Thieme Verlag KG 01.08.2023
• Subjects: continuous process; essential medicine; flow chemistry; optimization; Praziquantel

Abstract Praziquantel (PZQ; Brand name: Biltricide) is categorized as an anthelminthic drug, and it is used for the treatment of Schistosomiasis and other parasitic infections. The World Health Organization (WHO) has classified it as one of the essential and emergency medicines needed across the glo...