Isolation and Structural Elucidation of Unreported Prenylhydroquinone Glycoside from Sedum kamtschaticum Leaves and Its Effect on Hyperphosphorylated Tau Production in Aβ1–42-Treated SH-SY5Y Cells

• Published in: Separations Vol. 10; no. 8; p. 428
• Main Authors: Lee, Seung-Eun, Jeong, Se Yun, Jang, Yoon Seo, Cho, Kwang-Jin, Lee, Jeonghoon, Lee, Yunji, Kim, Ki Hyun
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.08.2023
• Subjects: Accumulation; Alzheimer's disease; Biological activity; Blood circulation; Cell growth; Crassulaceae; Glycosides; Herbal medicine; Ions; Natural products; NMR; Nuclear magnetic resonance; Planar structures; prenylhydroquinone glycoside; Sedum kamtschaticum; SH-SY5Y cells; Spectrum analysis; structural elucidation; tau; United States > US; Japan

Sedum kamtschaticum Fischer, of the Crassulaceae family, is a perennial and medicinal plant used in Asian folk medicine to alleviate inflammatory disease and improve blood circulation. As part of our ongoing exploration into natural products, seeking to identifying bioactive compounds, we characteri...