Fertility Preservation in Pediatric and Adolescent Oncology Patients: The Decision-Making Process of Parents

• Published in: Journal of adolescent and young adult oncology Vol. 6; no. 2; p. 213
• Main Authors: Li, Nancy, Jayasinghe, Yasmin, Kemertzis, Matthew A, Moore, Paddy, Peate, Michelle
• Format: Journal Article
• Language: English
• Published: United States 01.06.2017
• Subjects: Adolescent; Adult; Child; Conflict (Psychology); Decision Making; Emotions; Fertility Preservation; Humans; Medical Oncology; Neoplasms - therapy; Parents; Young Adult; oncofertility; quality of life; fertility; pediatric
• DOI: 10.1089/jayao.2016.0061

Decisions surrounding fertility preservation (FP) in children, adolescents, and adults can be difficult due to the distress of a cancer diagnosis, time constraints for decision-making, and lack of efficacy data. This review examines the decision-making process of oncology patients and their parents (if patients are in the pediatric or adolescent population) to better understand experiences of decisional conflict and regret. Two electronic databases, Embase and Pubmed, were searched using the terms (Decision-making OR Conflict (Psychology) OR Decision regret) AND (Freezing OR Oocyte OR Ovarian tissue OR Semen preservation OR Fertility preservation OR Cryopreservation) AND (Neoplasms OR Cancer OR Chemotherapy OR Drug therapy OR Radiotherapy). Medical Subject Heading terms were utilized where possible. Included articles discussed FP decision-making from the patient's perspective. Thirty-five articles discussing FP decision-making were included (24 in the adult population, 11 in the pediatric and adolescent population). Key themes from these articles included the following: factors considered in FP decision-making, decision-making in established procedures and experimental procedures, decisional conflict and regret, the perceived importance of information, adolescent involvement in decision-making, and ethical considerations in the pediatric population. Unique ethical issues arise in the pediatric and adolescent population. Considering that the decision to pursue FP is known to be difficult in the adult population, decisional conflict and regret may be greater for parents who are making the decision for their child.