Effect of primycin on growth-arrested cultures and cell integrity of Staphylococcus aureus

• Published in: Acta microbiologica et immunologica Hungarica Vol. 64; no. 2; p. 121
• Main Authors: Feiszt, Péter, Schneider, György, Emődy, Levente
• Format: Journal Article
• Language: English
• Published: Hungary 01.06.2017
• Subjects: Anti-Bacterial Agents - pharmacology; Humans; Macrolides - pharmacology; Microbial Sensitivity Tests; Staphylococcal Infections - microbiology; Staphylococcus aureus - drug effects; Staphylococcus aureus - growth & development; growth arrest; primycin; time-kill; no bacteriolysis; TEM; Staphylococcus aureus

Bactericidal effect against non-dividing bacteria is a very advantageous, but rare characteristic among antimicrobial agents, mostly possessed by those affecting the cell membrane. These kinds of agents can kill bacterial cells without lysis. We assessed these characteristics on primycin, a topical...