Genetic and Antigenic Variability in VP4 and VP7 of Group A Human Rotavirus in Yunnan, China, from 2015 to 2020

• Published in: Intervirology Vol. 68; no. 1; pp. 43 - 56
• Main Authors: Ma, Haoyu, Wang, Meifen, Chuan, Liufang, Long, Shuying, Qiu, Lijuan, Zhao, Canchun, Sun, Qiangming, Zhang, Zhen, Jiang, Hongchao
• Format: Journal Article
• Language: English
• Published: Switzerland S. Karger AG 29.04.2025
• Subjects: Antigenic Variation; Antigens, Viral - genetics; Antigens, Viral - immunology; Capsid Proteins - genetics; Capsid Proteins - immunology; Child, Preschool; China - epidemiology; Epitopes - genetics; Feces - virology; Genetic Variation; Genotype; Humans; Infant; Phylogeny; Prevalence; Rotavirus - classification; Rotavirus - genetics; Rotavirus - immunology; Rotavirus - isolation & purification; Rotavirus Infections - epidemiology; Rotavirus Infections - virology; Sequence Analysis, DNA; China; Phylogenetic analysis; Prevalence; Rotavirus A; Antigen epitope variation

Background: Rotavirus (RV) A is one of the major reasons which causes acute dehydration and diarrhea. It is also one of the highest morbid diseases in children. There are only a few reports about the changes in prevalence and VP4/VP7 genotype of RVs in southwest China. Here is the report about the p...