Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of HSK39297 in Chinese Healthy Subjects: A Phase 1 Clinical Trial - Dai, Yuyang; Wu, Feng; Ni, Siyang; Hu, Xiaojun; Han, Ying; Jiao, Ying; Lu, Huan; Liu, Yilin; Wang, Lingling; Lin, Yunfei; Chen, Meixia; Wang, Chao; et al. (Clinical and translational science, 2025)
Keywords: Administration, Oral; Adult; Area Under Curve; Asian People; China; Complement Inactivating Agents - administration & dosage; Complement Inactivating Agents - adverse effects; Complement Inactivating Agents - pharmacokinetics; Dose-Response Relationship, Drug; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Young Adult; China; pharmacokinetics; complement factor B inhibitor; glomerular diseases; complement system; pharmacodynamics; safety