Study of Th1/Th2 balance in peripheral blood mononuclear cells of patients with alopecia areata

• Published in: Acta microbiologica et immunologica Hungarica Vol. 62; no. 3; p. 275
• Main Authors: Sadeghi, Soha, Sanati, Mohammad Hossein, Taghizadeh, Morteza, Mansouri, Parvine, Jadali, Zohreh
• Format: Journal Article
• Language: English
• Published: Hungary 01.09.2015
• Subjects: Adolescent; Adult; Alopecia Areata - genetics; Alopecia Areata - immunology; Female; GATA3 Transcription Factor - genetics; GATA3 Transcription Factor - immunology; Humans; Interferon-gamma - genetics; Interferon-gamma - immunology; Interleukin-4 - genetics; Interleukin-4 - immunology; Leukocytes, Mononuclear - immunology; Male; T-Box Domain Proteins - genetics; T-Box Domain Proteins - immunology; Th1 Cells - immunology; Th2 Cells - immunology; Young Adult; cytokine; T lymphocyte; autoimmunity; alopecia areata

Alopecia areata represents an autoimmune pathological process driven primarily by cellular aberrations contained within the immune system, which activates various humoral and cellular elements of the immune response. The aim of this study was to determine the mRNA expression levels of T-bet and GATA...