T cells participate in bone remodeling during the rapid palatal expansion

• Published in: The FASEB journal Vol. 34; no. 11; p. 15327
• Main Authors: Li, Jing, Yu, Ting-Ting, Yan, Hui-Chun, Qiao, Yi-Qiang, Wang, Lin-Chuan, Zhang, Ting, Li, Qian, Zhou, Yan-Heng, Liu, Da-Wei
• Format: Journal Article
• Language: English
• Published: United States 01.11.2020
• Subjects: Animals; Bone Remodeling; Male; Mice; Mice, Inbred C57BL; Osteoclasts - cytology; Osteoclasts - immunology; Osteogenesis; Palatal Expansion Technique; Palate - cytology; Palate - immunology; T-Lymphocytes, Regulatory - immunology; Th1 Cells - immunology; Th17 Cells - immunology; orthodontics; bone formation; immunity; osteoclasts
• ISSN: 1530-6860
• DOI: 10.1096/fj.202001078R

Palatal expansion has been widely used for the treatment of transverse discrepancy or maxillae hypoplasia, but the biological mechanism of bone formation during this procedure is largely unknown. Osteoclasts, which could be regulated by T cells and other components of the immune system, play a cruci...