Endocuff‐assisted colonoscopy versus cap‐assisted colonoscopy for adenoma detection rate: A meta‐analysis of randomized controlled trials
Background and Aims Add‐on devices have been widely used in clinical practice. The aim of this meta‐analysis was to compare the adenoma detection rate between Endocuff‐assisted colonoscopy (EAC) and cap‐assisted colonoscopy (CAC). Methods PubMed, EMBASE, SCOPUS, and Cochrane databases were searched....
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Published in | Journal of gastroenterology and hepatology Vol. 35; no. 12; pp. 2066 - 2073 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
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Wiley Subscription Services, Inc
01.12.2020
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Abstract | Background and Aims
Add‐on devices have been widely used in clinical practice. The aim of this meta‐analysis was to compare the adenoma detection rate between Endocuff‐assisted colonoscopy (EAC) and cap‐assisted colonoscopy (CAC).
Methods
PubMed, EMBASE, SCOPUS, and Cochrane databases were searched. Outcomes included adenoma detection rate, cecal intubation rate, cecal intubation time, and withdrawal time. Dichotomous data were pooled to obtain the odds ratio or risk ratio. Continuous data were pooled using the mean difference.
Results
Of the 240 articles reviewed, six randomized controlled trials were included, with a total of 1994 patients. In the meta‐analysis, no statistical difference in adenoma detection rate was detected between EAC and CAC (47.0% vs 45.1%; P = 0.33). EAC significantly improved detection rate of diminutive adenomas/polyps compared with CAC (P = 0.01). Cecal intubation was achieved in 96.5% in EAC group and 97.9% in CAC group (P = 0.04). Besides, no statistical difference was found in cecal intubation time (P = 0.86), withdrawal time (P = 0.88), small adenomas/polyps (P = 0.60), or large adenomas/polyps (P = 0.95).
Conclusion
EAC and CAC have their respective merits. EAC significantly improve the detection of diminutive adenomas/polyps. CAC was better in cecal intubation rate. |
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AbstractList | Background and Aims
Add‐on devices have been widely used in clinical practice. The aim of this meta‐analysis was to compare the adenoma detection rate between Endocuff‐assisted colonoscopy (EAC) and cap‐assisted colonoscopy (CAC).
Methods
PubMed, EMBASE, SCOPUS, and Cochrane databases were searched. Outcomes included adenoma detection rate, cecal intubation rate, cecal intubation time, and withdrawal time. Dichotomous data were pooled to obtain the odds ratio or risk ratio. Continuous data were pooled using the mean difference.
Results
Of the 240 articles reviewed, six randomized controlled trials were included, with a total of 1994 patients. In the meta‐analysis, no statistical difference in adenoma detection rate was detected between EAC and CAC (47.0% vs 45.1%; P = 0.33). EAC significantly improved detection rate of diminutive adenomas/polyps compared with CAC (P = 0.01). Cecal intubation was achieved in 96.5% in EAC group and 97.9% in CAC group (P = 0.04). Besides, no statistical difference was found in cecal intubation time (P = 0.86), withdrawal time (P = 0.88), small adenomas/polyps (P = 0.60), or large adenomas/polyps (P = 0.95).
Conclusion
EAC and CAC have their respective merits. EAC significantly improve the detection of diminutive adenomas/polyps. CAC was better in cecal intubation rate. Add-on devices have been widely used in clinical practice. The aim of this meta-analysis was to compare the adenoma detection rate between Endocuff-assisted colonoscopy (EAC) and cap-assisted colonoscopy (CAC). PubMed, EMBASE, SCOPUS, and Cochrane databases were searched. Outcomes included adenoma detection rate, cecal intubation rate, cecal intubation time, and withdrawal time. Dichotomous data were pooled to obtain the odds ratio or risk ratio. Continuous data were pooled using the mean difference. Of the 240 articles reviewed, six randomized controlled trials were included, with a total of 1994 patients. In the meta-analysis, no statistical difference in adenoma detection rate was detected between EAC and CAC (47.0% vs 45.1%; P = 0.33). EAC significantly improved detection rate of diminutive adenomas/polyps compared with CAC (P = 0.01). Cecal intubation was achieved in 96.5% in EAC group and 97.9% in CAC group (P = 0.04). Besides, no statistical difference was found in cecal intubation time (P = 0.86), withdrawal time (P = 0.88), small adenomas/polyps (P = 0.60), or large adenomas/polyps (P = 0.95). EAC and CAC have their respective merits. EAC significantly improve the detection of diminutive adenomas/polyps. CAC was better in cecal intubation rate. Add-on devices have been widely used in clinical practice. The aim of this meta-analysis was to compare the adenoma detection rate between Endocuff-assisted colonoscopy (EAC) and cap-assisted colonoscopy (CAC).BACKGROUND AND AIMSAdd-on devices have been widely used in clinical practice. The aim of this meta-analysis was to compare the adenoma detection rate between Endocuff-assisted colonoscopy (EAC) and cap-assisted colonoscopy (CAC).PubMed, EMBASE, SCOPUS, and Cochrane databases were searched. Outcomes included adenoma detection rate, cecal intubation rate, cecal intubation time, and withdrawal time. Dichotomous data were pooled to obtain the odds ratio or risk ratio. Continuous data were pooled using the mean difference.METHODSPubMed, EMBASE, SCOPUS, and Cochrane databases were searched. Outcomes included adenoma detection rate, cecal intubation rate, cecal intubation time, and withdrawal time. Dichotomous data were pooled to obtain the odds ratio or risk ratio. Continuous data were pooled using the mean difference.Of the 240 articles reviewed, six randomized controlled trials were included, with a total of 1994 patients. In the meta-analysis, no statistical difference in adenoma detection rate was detected between EAC and CAC (47.0% vs 45.1%; P = 0.33). EAC significantly improved detection rate of diminutive adenomas/polyps compared with CAC (P = 0.01). Cecal intubation was achieved in 96.5% in EAC group and 97.9% in CAC group (P = 0.04). Besides, no statistical difference was found in cecal intubation time (P = 0.86), withdrawal time (P = 0.88), small adenomas/polyps (P = 0.60), or large adenomas/polyps (P = 0.95).RESULTSOf the 240 articles reviewed, six randomized controlled trials were included, with a total of 1994 patients. In the meta-analysis, no statistical difference in adenoma detection rate was detected between EAC and CAC (47.0% vs 45.1%; P = 0.33). EAC significantly improved detection rate of diminutive adenomas/polyps compared with CAC (P = 0.01). Cecal intubation was achieved in 96.5% in EAC group and 97.9% in CAC group (P = 0.04). Besides, no statistical difference was found in cecal intubation time (P = 0.86), withdrawal time (P = 0.88), small adenomas/polyps (P = 0.60), or large adenomas/polyps (P = 0.95).EAC and CAC have their respective merits. EAC significantly improve the detection of diminutive adenomas/polyps. CAC was better in cecal intubation rate.CONCLUSIONEAC and CAC have their respective merits. EAC significantly improve the detection of diminutive adenomas/polyps. CAC was better in cecal intubation rate. Background and AimsAdd‐on devices have been widely used in clinical practice. The aim of this meta‐analysis was to compare the adenoma detection rate between Endocuff‐assisted colonoscopy (EAC) and cap‐assisted colonoscopy (CAC).MethodsPubMed, EMBASE, SCOPUS, and Cochrane databases were searched. Outcomes included adenoma detection rate, cecal intubation rate, cecal intubation time, and withdrawal time. Dichotomous data were pooled to obtain the odds ratio or risk ratio. Continuous data were pooled using the mean difference.ResultsOf the 240 articles reviewed, six randomized controlled trials were included, with a total of 1994 patients. In the meta‐analysis, no statistical difference in adenoma detection rate was detected between EAC and CAC (47.0% vs 45.1%; P = 0.33). EAC significantly improved detection rate of diminutive adenomas/polyps compared with CAC (P = 0.01). Cecal intubation was achieved in 96.5% in EAC group and 97.9% in CAC group (P = 0.04). Besides, no statistical difference was found in cecal intubation time (P = 0.86), withdrawal time (P = 0.88), small adenomas/polyps (P = 0.60), or large adenomas/polyps (P = 0.95).ConclusionEAC and CAC have their respective merits. EAC significantly improve the detection of diminutive adenomas/polyps. CAC was better in cecal intubation rate. |
Author | Wang, Peng Li, Ai Li, Yan‐Qing Zhou, Ru‐Chen Yang, Jing‐Ze Feng, Bing‐Cheng Yang, Xiao‐Xiao Qu, Jun‐Yan Li, Li‐Xiang Zhang, Ming‐Ming Zuo, Xiu‐Li |
Author_xml | – sequence: 1 givenname: Ai surname: Li fullname: Li, Ai organization: Shandong University – sequence: 2 givenname: Jing‐Ze surname: Yang fullname: Yang, Jing‐Ze organization: Shandong University – sequence: 3 givenname: Xiao‐Xiao surname: Yang fullname: Yang, Xiao‐Xiao organization: Shandong University – sequence: 4 givenname: Bing‐Cheng surname: Feng fullname: Feng, Bing‐Cheng organization: Shandong University – sequence: 5 givenname: Ming‐Ming surname: Zhang fullname: Zhang, Ming‐Ming organization: Shandong University – sequence: 6 givenname: Jun‐Yan surname: Qu fullname: Qu, Jun‐Yan organization: Shandong University – sequence: 7 givenname: Ru‐Chen surname: Zhou fullname: Zhou, Ru‐Chen organization: Shandong University – sequence: 8 givenname: Peng surname: Wang fullname: Wang, Peng organization: Shandong University – sequence: 9 givenname: Li‐Xiang surname: Li fullname: Li, Li‐Xiang organization: Shandong University – sequence: 10 givenname: Xiu‐Li orcidid: 0000-0001-9556-8771 surname: Zuo fullname: Zuo, Xiu‐Li organization: Shandong University – sequence: 11 givenname: Yan‐Qing orcidid: 0000-0001-9325-4808 surname: Li fullname: Li, Yan‐Qing email: liyanqing@sdu.edu.cn organization: Shandong University |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32562282$$D View this record in MEDLINE/PubMed |
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CitedBy_id | crossref_primary_10_1016_j_tige_2021_06_007 crossref_primary_10_1080_17474124_2023_2273990 crossref_primary_10_1016_j_cgh_2021_12_037 crossref_primary_10_1002_ueg2_12078 crossref_primary_10_1111_jgh_15321 crossref_primary_10_1016_j_gie_2022_08_030 |
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Keywords | Endocuff adenoma detection rate colorectal cancer cap-assisted colonoscopy |
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Notes | We declare that we have no conflict of interests. Ai Li and Jing‐Ze Yang were responsible for analyzing the data and drafting the manuscript. Xiao‐Xiao Yang, Ru‐Chen Zhou and Bing‐Cheng Feng were involved in data collection. Ming‐Ming Zhang, Jun‐Yan Qu, Peng Wang and Li‐Xiang Li interpreted the data. Xiu‐Li Zuo and Yan‐Qing Li provided critical revision of the manuscript. All of the authors read and approved the final manuscript. Declaration of conflict of interest This study was supported by the National Natural Science Foundation of China (81873550), Key Research and Development Program of Shandong Province (2018CXGC1209), and Natural Science Foundation of Shandong Province (ZR2016HB62) This study is also supported by the Taishan Scholars Program of Shandong Province (20181219). Financial support Author contributions ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 |
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Add‐on devices have been widely used in clinical practice. The aim of this meta‐analysis was to compare the adenoma detection rate between... Add-on devices have been widely used in clinical practice. The aim of this meta-analysis was to compare the adenoma detection rate between Endocuff-assisted... Background and AimsAdd‐on devices have been widely used in clinical practice. The aim of this meta‐analysis was to compare the adenoma detection rate between... |
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SubjectTerms | Adenoma adenoma detection rate cap‐assisted colonoscopy Cecum Clinical trials Colon Colonoscopy colorectal cancer Endocuff Intubation Meta-analysis Polyps Statistics Tumors |
Title | Endocuff‐assisted colonoscopy versus cap‐assisted colonoscopy for adenoma detection rate: A meta‐analysis of randomized controlled trials |
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