Consanguinity and the Risk of Hashimoto's Thyroiditis

• Published in: Thyroid (New York, N.Y.) Vol. 27; no. 3; p. 390
• Main Authors: Zaghlol, Raja Y, Haghighi, Alireza, Alkhayyat, Motasem M, Theyab, Othman F, Owaydah, Amal M, Massad, Mu'taz M, Atari, Mohammad A, Zayed, Ayman A
• Format: Journal Article
• Language: English
• Published: United States 01.03.2017
• Subjects: Adult; Case-Control Studies; Consanguinity; Female; Genetic Predisposition to Disease; Hashimoto Disease - genetics; Humans; Hypothyroidism - genetics; Jordan; Male; Middle Aged; Odds Ratio; Risk Factors; thyroid peroxidase antibodies; genetics; autoimmune thyroiditis; consanguinity; hypothyroidism; case control; Hashimoto's thyroiditis

Hashimoto's thyroiditis (HT) is the most common autoimmune thyroid disease that may lead to hypothyroidism due to progressive destruction of the thyroid. The etiology of HT is unclear. However, it is associated with multiple genetic predispositions. Consanguinity has been associated with an inc...