Exosomes Derived from Hypoxia-Treated Human Adipose Mesenchymal Stem Cells Enhance Angiogenesis Through the PKA Signaling Pathway

• Published in: Stem cells and development Vol. 27; no. 7; p. 456
• Main Authors: Xue, Chunling, Shen, Yamei, Li, Xuechun, Li, Ba, Zhao, Sun, Gu, Junjie, Chen, Yunfei, Ma, Baitao, Wei, Junji, Han, Qin, Zhao, Robert C
• Format: Journal Article
• Language: English
• Published: United States 01.04.2018
• Subjects: animal models; hypoxic exosomes; VEGF; angiogenesis; mesenchymal stem cells

Angiogenesis is a complicated and sequential process that plays an important role in different physiological processes. Mesenchymal stem cells (MSCs), which are pluripotent stem cells, are widely used for the treatment of ischemic and traumatic diseases, and exosomes derived from these cells can als...