Inflammatory, oxidative stress and cognitive functions in patients under maintenance treatment with methadone or buprenorphine and healthy subjects

• Published in: Journal of clinical neuroscience Vol. 101; pp. 57 - 62
• Main Authors: Arezoomandan, Mohammad, Zhiani, Rahele, Mehrzad, Jamshid, Motavalizadehkakhky, Alireza, Eshrati, Sahar, Arezoomandan, Reza
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.07.2022
• Subjects: Analgesics, Opioid - therapeutic use; Antioxidants; Buprenorphine; Buprenorphine - pharmacology; Buprenorphine - therapeutic use; C-Reactive Protein; Cognition; Cognitive function; Ferritins; Healthy Volunteers; Humans; Maintenance treatment; Methadone; Methadone - therapeutic use; Opioids; Oxidative Stress; Oxidative stress; Methadone; Buprenorphine; Cognitive function; Maintenance treatment; Opioids
• ISSN: 0967-5868; 1532-2653; 1532-2653
• DOI: 10.1016/j.jocn.2022.04.018

•MMP and BMP showed cognitive impairment compared to healthy participants.•MMP and BMP had severe oxidative stress and inflammation compared to healthy participants.•BMP showed higher oxidative stress compared to the MMP.•The level of inflammation was higher in MMP compared to the BMP.•Executive fun...