Efficacy of rhBMP-2/Hydroxyapatite on Sinus Floor Augmentation A Multicenter, Randomized Controlled Clinical Trial

• Published in: Journal of dental research Vol. 94; no. 9_suppl; pp. 158S - 165S
• Main Authors: Kim, H.J., Chung, J.H., Shin, S.Y., Shin, S.I., Kye, S.B., Kim, N.K., Kwon, T.G., Paeng, J.Y., Kim, J.W., Oh, O.H., Kook, M.S., Yang, H.J., Hwang, S.J.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.09.2015
• Subjects: Animals; Biopsy - methods; Bone Morphogenetic Protein 2 - therapeutic use; Bone Substitutes - therapeutic use; Bone Transplantation - methods; Cattle; Female; Heterografts - pathology; Heterografts - transplantation; Humans; Hydroxyapatites - therapeutic use; Male; Maxillary Sinus - pathology; Middle Aged; Osteogenesis - physiology; Prospective Studies; Recombinant Proteins - therapeutic use; Safety; Single-Blind Method; Sinus Floor Augmentation - methods; Transforming Growth Factor beta - therapeutic use; Treatment Outcome; biopsy; comparative study; bone morphogenetic protein 2; clinical efficacy; osteogenesis; Escherichia coli

The aim of this randomized single-blinded active-controlled clinical study was to evaluate the early efficacy of low-dose Escherichia coli–derived recombinant human bone morphogenetic protein 2 (rhBMP-2) soaked with hydroxyapatite granules (BMP-2/H) as compared with an inorganic bovine bone xenograf...