Can malignant thyroid nodules be distinguished from benign thyroid nodules in children and adolescents by clinical characteristics? A review of 89 pediatric patients with thyroid nodules

• Published in: Thyroid (New York, N.Y.) Vol. 25; no. 4; p. 392
• Main Authors: Buryk, Melissa A, Simons, Jeffrey P, Picarsic, Jennifer, Monaco, Sara E, Ozolek, John A, Joyce, Judith, Gurtunca, Nursen, Nikiforov, Yuri E, Feldman Witchel, Selma
• Format: Journal Article
• Language: English
• Published: United States 01.04.2015
• Subjects: Adenocarcinoma, Follicular - diagnostic imaging; Adenocarcinoma, Follicular - genetics; Adenocarcinoma, Follicular - pathology; Adolescent; Age Factors; Biomarkers, Tumor - genetics; Biopsy, Fine-Needle; Carcinoma - diagnostic imaging; Carcinoma - genetics; Carcinoma - pathology; Carcinoma, Papillary; Child; Diagnosis, Differential; Female; Hospitals, Pediatric; Humans; Male; Molecular Diagnostic Techniques; Pennsylvania; Predictive Value of Tests; Prognosis; Retrospective Studies; Thyroid Cancer, Papillary; Thyroid Neoplasms - diagnostic imaging; Thyroid Neoplasms - genetics; Thyroid Neoplasms - pathology; Thyroid Nodule - diagnostic imaging; Thyroid Nodule - genetics; Thyroid Nodule - pathology; Time Factors; Tumor Burden; Ultrasonography; Pennsylvania

Thyroid nodules are less common in children than adults, but the risk of malignancy in thyroid nodules is much higher in children. The ability to characterize pediatric thyroid nodules has improved with the use of ultrasound-guided fine-needle aspiration, the Bethesda System for Reporting Thyroid Cy...