Effect of Long-Term Recombinant Growth Hormone Therapy in Children - The National Cooperative Growth Study, USA, 1985-1994

• Published in: Journal of Pediatric Endocrinology and Metabolism Vol. 11; no. 3; pp. 403 - 412
• Main Authors: Root, A. W., Kemp, S.F., Rundle, A.C., Dana, K., Attie, K.M., National Cooperative Growth Study
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 1998
• Subjects: Adolescent; Body Height - drug effects; Child; Drug Administration Schedule; Female; Growth Disorders - drug therapy; Human Growth Hormone - administration & dosage; Human Growth Hormone - blood; Human Growth Hormone - deficiency; Human Growth Hormone - therapeutic use; Humans; Injections; Longitudinal Studies; Male; Osmolar Concentration; Recombinant Proteins - administration & dosage; Recombinant Proteins - therapeutic use; Time Factors; Treatment Outcome; Turner Syndrome - drug therapy

Over a 9-year period (1985-1994) approximately 20,000 children received recombinant human growth hormone (rhGH) while enrolled in the National Cooperative Growth Study (NCGS), an observational, longitudinal study designed to monitor the long term efficacy and safety of rhGH administered to children...