Expression of Hematopoietic Stem and Endothelial Cell Markers in Canine Hemangiosarcoma

• Published in: Toxicologic pathology Vol. 48; no. 3; p. 481
• Main Authors: Kakiuchi-Kiyota, Satoko, Obert, Leslie A, Crowell, Danielle M, Xia, Shuhua, Roy, Marc D, Coskran, Timothy M, Kreeger, John M, Crabbs, Torrie A, Cohen, Samuel M, Cattley, Russell C, Cook, Jon C
• Format: Journal Article
• Language: English
• Published: United States 01.04.2020
• Subjects: canine; immunohistochemistry; hematopoietic stem cells; endothelial progenitor cells; tumor; hemangiosarcoma

Several chemicals and pharmaceuticals increase the incidence of hemangiosarcomas (HSAs) in mice, but the relevance to humans is uncertain. Recently, canine HSAs were identified as a powerful tool for investigating the pathogenesis of human HSAs. To characterize the cellular phenotype of canine HSAs,...