Interethnic Variability in CYP2D6, CYP2C9, and CYP2C19 Genes and Predicted Drug Metabolism Phenotypes Among 6060 Ibero- and Native Americans: RIBEF-CEIBA Consortium Report on Population Pharmacogenomics

• Published in: Omics (Larchmont, N.Y.) Vol. 22; no. 9; p. 575
• Main Authors: Naranjo, María-Eugenia G, Rodrigues-Soares, Fernanda, Peñas-Lledó, Eva M, Tarazona-Santos, Eduardo, Fariñas, Humberto, Rodeiro, Idania, Terán, Enrique, Grazina, Manuela, Moya, Graciela E, López-López, Marisol, Sarmiento, Alba P, Calzadilla, Luis R, Ramírez-Roa, Ronald, Ortiz-López, Rocío, Estévez-Carrizo, Francisco E, Sosa-Macías, Martha, Barrantes, Ramiro, LLerena, Adrián
• Format: Journal Article
• Language: English
• Published: United States 01.09.2018
• Subjects: Amerindians; CYP2C9; CYP2D6; drug metabolism; Latin Americans; precision medicine; CYP2C19; pharmacogenetics

Pharmacogenetic variation in Latin Americans is understudied, which sets a barrier for the goal of global precision medicine. The RIBEF-CEIBA Network Consortium was established to characterize interindividual and between population variations in CYP2D6, CYP2C9, and CYP2C19 drug metabolizing enzyme g...