Platypnea-orthodeoxia Syndrome Diagnosed Using Contrast Transesophageal Echocardiography with Simultaneous SpO2 Monitoring

Platypnea-orthodeoxia syndrome (POS) is a rare condition characterized by interatrial right-to-left shunting that is exacerbated in the upright position. We herein report a 78-year-old woman with POS that remained undiagnosed for 2 years, despite repetitive transthoracic echocardiography (TTE). POS...

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Published inInternal Medicine Vol. 55; no. 16; pp. 2203 - 2207
Main Authors Sekihara, Takayuki, Kimura, Masahiro, Hazama, Daisuke, Kimura, Yuki, Hayashi, Hideyuki, Okano, Mitsumasa, Funasako, Moritoshi, Sasaki, Kenichi, Nakane, Eisaku, Miyamoto, Shoichi, Izumi, Toshiaki, Haruna, Tetsuya, Fukui, Motonari, Inoko, Moriaki
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 2016
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Abstract Platypnea-orthodeoxia syndrome (POS) is a rare condition characterized by interatrial right-to-left shunting that is exacerbated in the upright position. We herein report a 78-year-old woman with POS that remained undiagnosed for 2 years, despite repetitive transthoracic echocardiography (TTE). POS was ultimately diagnosed using contrast transesophageal echocardiography (TEE), which revealed a marked increase in right-to-left shunting in the sitting position, associated with simultaneous desaturation. Therefore, we propose that POS should be considered according to the clinical symptoms, regardless of the repetitive TTE results, and contrast TEE should be performed in both the supine and sitting positions to exclude a diagnosis of POS.
AbstractList Platypnea-orthodeoxia syndrome (POS) is a rare condition characterized by interatrial right-to-left shunting that is exacerbated in the upright position. We herein report a 78-year-old woman with POS that remained undiagnosed for 2 years, despite repetitive transthoracic echocardiography (TTE). POS was ultimately diagnosed using contrast transesophageal echocardiography (TEE), which revealed a marked increase in right-to-left shunting in the sitting position, associated with simultaneous desaturation. Therefore, we propose that POS should be considered according to the clinical symptoms, regardless of the repetitive TTE results, and contrast TEE should be performed in both the supine and sitting positions to exclude a diagnosis of POS.
Author Sasaki, Kenichi
Miyamoto, Shoichi
Hazama, Daisuke
Kimura, Yuki
Haruna, Tetsuya
Inoko, Moriaki
Funasako, Moritoshi
Fukui, Motonari
Kimura, Masahiro
Sekihara, Takayuki
Okano, Mitsumasa
Nakane, Eisaku
Hayashi, Hideyuki
Izumi, Toshiaki
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10.1161/hc3101.093603
10.1016/j.jcmg.2012.01.015
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References 1. Shiraishi Y, Hakuno D, Isoda K, Miyazaki K, Adachi T. Platypnea-orthodeoxia syndrome due to PFO and aortic dilation. JACC Cardiovasc Imaging 5: 570-571, 2012.
5. Sanikommu V, Lasorda D, Poornima I. Anatomical factors triggering platypnea-orthodeoxia in adults. Clin Cardiol 32: E55-E57, 2009.
2. Medina A, de Lezo JS, Caballero E, Ortega JR. Platypnea-orthodeoxia due to aortic elongation. Circulation 104: 741, 2001.
4. Kotoulas C, Patris K, Tsintiris K, Zoumboulides A, Lazarides K, Laoutides G. Platypnea-orthodeoxia syndrome after pneumonectomy relieved by mediastinal repositioning. Ann Thorac Surg 83: 1524-1526, 2007.
6. Knapper JT, Schultz J, Das G, Sperling LS. Cardiac platypnea-orthodeoxia syndrome: an often unrecognized malady. Clin Cardiol 37: 645-649, 2014.
7. Mojadidi MK, Gevorgyan R, Noureddin N, Tobis JM. The effect of patent foramen ovale closure in patients with platypnea-orthodeoxia syndrome. Catheter Cardiovasc Interv 86: 701-707, 2015.
3. Fukuoka R, Kawasaki T, Koga H, et al. Platypnea-orthodeoxia syndrome associated with a thoracic vertebral fracture following a car accident. Intern Med 53: 35-38, 2014.
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SubjectTerms Aged
contrast echocardiography
Dyspnea - diagnosis
Echocardiography, Transesophageal
Female
Heart Diseases - diagnosis
Heart Diseases - diagnostic imaging
Humans
Oxygen - blood
platypnea-orthodeoxia syndrome
Posture
Syndrome
transesophageal echocardiography
Title Platypnea-orthodeoxia Syndrome Diagnosed Using Contrast Transesophageal Echocardiography with Simultaneous SpO2 Monitoring
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