Non-destructive diagnostic testing of cardiac myxoma by serum confocal Raman microspectroscopy combined with multivariate analysis

• Published in: Analytical methods Vol. 15; no. 21; pp. 2578 - 2587
• Main Authors: Chen, Qiang, Shi, Tao, Du, Dan, Wang, Bo, Zhao, Sha, Gao, Yang, Wang, Shuang, Zhang, Zhanqin
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 01.06.2023
• Subjects: Algorithms; Diagnosis; Diagnostic Techniques and Procedures; Diagnostic tests; Discriminant Analysis; Fatty acids; Heart; Heart Neoplasms; Humans; Kernel functions; Labeling; Multivariate Analysis; Myxoma; Nondestructive testing; Phenylalanine; Polynomials; Principal components analysis; Radial basis function; Raman spectra; Raman spectroscopy; Respiratory Tract Neoplasms; Serum levels; Signs and symptoms; Spectrum analysis; Spectrum Analysis, Raman; Support vector machines; Tumors; Vibrations

The symptoms of cardiac myxoma (CM) mainly occur when the tumor is growing, and the diagnosis is determined by clinical presentation. Unfortunately, there is no evidence that specific blood tests are useful in CM diagnosis. Raman spectroscopy (RS) has emerged as a promising auxiliary diagnostic tool...