Long-Term Efficacy of Oral Vancomycin Prophylaxis for the Prevention of Clostridium difficile Recurrence

• Published in: Journal of pharmacy practice Vol. 33; no. 5; p. 633
• Main Authors: Knight, Emmanuel M, Schiller, Daryl S, Fulman, Magda K, Rastogi, Rupangi
• Format: Journal Article
• Language: English
• Published: United States 01.10.2020
• Subjects: Anti-Bacterial Agents - therapeutic use; Clostridioides difficile; Clostridium Infections - drug therapy; Clostridium Infections - epidemiology; Clostridium Infections - prevention & control; Humans; Recurrence; Retrospective Studies; Vancomycin; vancomycin; prophylaxis; recurrent; Clostridium difficile; infectious diseases

Limited evidence suggests that prophylactic oral vancomycin may be beneficial in preventing infection (CDI) recurrence, but long-term efficacy is unknown. To evaluate the long-term efficacy of oral vancomycin prophylaxis (OVP) in preventing CDI recurrence in subjects who require subsequent antibioti...