Impact of serous macular detachment on visual recovery in retinal vein occlusion treatment
The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results. A total of 117 eyes from 115 patients who had been treated with intravitreal injections for macular edema secondary to retinal vein occlusion were retrospectivel...
Saved in:
| Published in | Arquivos brasileiros de oftalmologia Vol. 85; no. 5; pp. 606 - 613 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English Portuguese |
| Published |
Brazil
Conselho Brasileiro de Oftalmologia
01.01.2022
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results.
A total of 117 eyes from 115 patients who had been treated with intravitreal injections for macular edema secondary to retinal vein occlusion were retrospectively reviewed. Visual acuity, optical coherence tomography, and fundus fluorescein angiography findings were evaluated according to the status of serous macular detachment.
In the branch retinal vein occlusion group, a statistically significant increase was detected in the mean visual acuity compared to the baseline value at each visit in the absence of serous macular detachment, whereas the increase in the mean visual acuity was significant only at the 3- and 6-month visits in the presence of serous macular detachment. In the central retinal vein occlusion group, there was an increase in the mean visual acuity compared to the baseline value at every visit in the absence of serous macular detachment, whereas the mean visual acuity decreased compared to the baseline value at every visit except at the 3-month visit in the presence of serous macular detachment. The ellipsoid zone defect was more prominent in the presence of serous macular detachment in eyes with branch retinal vein occlusion, whereas there was no significant difference in the ellipsoid zone in the absence or presence of serous macular detachment in eyes with central retinal vein occlusion.
In the group with macular edema due to retinal vein occlusion, the initial mean visual acuity increase observed in the first year was maintained in cases without serous macular detachment but not in those with serous macular detachment. Serous macular detachment could be a negative factor in eyes with retinal vein occlusion. |
|---|---|
| AbstractList | ABSTRACT Purpose: The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results. Methods: A total of 117 eyes from 115 patients who had been treated with intravitreal injections for macular edema secondary to retinal vein occlusion were retrospectively reviewed. Visual acuity, optical coherence tomography, and fundus fluorescein angiography findings were evaluated according to the status of serous macular detachment. Results: In the branch retinal vein occlusion group, a statistically significant increase was detected in the mean visual acuity compared to the baseline value at each visit in the absence of serous macular detachment, whereas the increase in the mean visual acuity was significant only at the 3- and 6-month visits in the presence of serous macular detachment. In the central retinal vein occlusion group, there was an increase in the mean visual acuity compared to the baseline value at every visit in the absence of serous macular detachment, whereas the mean visual acuity decreased compared to the baseline value at every visit except at the 3-month visit in the presence of serous macular detachment. The ellipsoid zone defect was more prominent in the presence of serous macular detachment in eyes with branch retinal vein occlusion, whereas there was no significant difference in the ellipsoid zone in the absence or presence of serous macular detachment in eyes with central retinal vein occlusion. Conclusions: In the group with macular edema due to retinal vein occlusion, the initial mean visual acuity increase observed in the first year was maintained in cases without serous macular detachment but not in those with serous macular detachment. Serous macular detachment could be a negative factor in eyes with retinal vein occlusion. The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results. A total of 117 eyes from 115 patients who had been treated with intravitreal injections for macular edema secondary to retinal vein occlusion were retrospectively reviewed. Visual acuity, optical coherence tomography, and fundus fluorescein angiography findings were evaluated according to the status of serous macular detachment. In the branch retinal vein occlusion group, a statistically significant increase was detected in the mean visual acuity compared to the baseline value at each visit in the absence of serous macular detachment, whereas the increase in the mean visual acuity was significant only at the 3- and 6-month visits in the presence of serous macular detachment. In the central retinal vein occlusion group, there was an increase in the mean visual acuity compared to the baseline value at every visit in the absence of serous macular detachment, whereas the mean visual acuity decreased compared to the baseline value at every visit except at the 3-month visit in the presence of serous macular detachment. The ellipsoid zone defect was more prominent in the presence of serous macular detachment in eyes with branch retinal vein occlusion, whereas there was no significant difference in the ellipsoid zone in the absence or presence of serous macular detachment in eyes with central retinal vein occlusion. In the group with macular edema due to retinal vein occlusion, the initial mean visual acuity increase observed in the first year was maintained in cases without serous macular detachment but not in those with serous macular detachment. Serous macular detachment could be a negative factor in eyes with retinal vein occlusion. PURPOSEThe aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results. METHODSA total of 117 eyes from 115 patients who had been treated with intravitreal injections for macular edema secondary to retinal vein occlusion were retrospectively reviewed. Visual acuity, optical coherence tomography, and fundus fluorescein angiography findings were evaluated according to the status of serous macular detachment. RESULTSIn the branch retinal vein occlusion group, a statistically significant increase was detected in the mean visual acuity compared to the baseline value at each visit in the absence of serous macular detachment, whereas the increase in the mean visual acuity was significant only at the 3- and 6-month visits in the presence of serous macular detachment. In the central retinal vein occlusion group, there was an increase in the mean visual acuity compared to the baseline value at every visit in the absence of serous macular detachment, whereas the mean visual acuity decreased compared to the baseline value at every visit except at the 3-month visit in the presence of serous macular detachment. The ellipsoid zone defect was more prominent in the presence of serous macular detachment in eyes with branch retinal vein occlusion, whereas there was no significant difference in the ellipsoid zone in the absence or presence of serous macular detachment in eyes with central retinal vein occlusion. CONCLUSIONSIn the group with macular edema due to retinal vein occlusion, the initial mean visual acuity increase observed in the first year was maintained in cases without serous macular detachment but not in those with serous macular detachment. Serous macular detachment could be a negative factor in eyes with retinal vein occlusion. |
| Author | Polat, Nihat Firat, Ilknur Tuncer Firat, Murat |
| AuthorAffiliation | Malatya Training and Research Hospital Inonu University School of Medicine |
| AuthorAffiliation_xml | – name: Malatya Training and Research Hospital – name: Inonu University School of Medicine |
| Author_xml | – sequence: 1 givenname: Ilknur Tuncer orcidid: 0000-0003-1491-8659 surname: Firat fullname: Firat, Ilknur Tuncer organization: Department of Ophthalmology, Inonu University School of Medicine, Malatya, Turkey – sequence: 2 givenname: Nihat surname: Polat fullname: Polat, Nihat organization: Department of Ophthalmology, Inonu University School of Medicine, Malatya, Turkey – sequence: 3 givenname: Murat surname: Firat fullname: Firat, Murat organization: Department of Ophthalmology, Malatya Training and Research Hospital, Malatya, Turkey |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35170645$$D View this record in MEDLINE/PubMed |
| BookMark | eNo9kctqwzAQRUVJaR7tD3RRvOzGqTSybGtZQh-BQBdtN90IRR5TB9tKJTuQv6-Mk4BAGume0cydOZm0tkVC7hldCsnFE6U0iSFL5BIoAKV5fkVmLM3yGCSICZldBFMy935HKSRSihsy5YJlNE3EjPysm702XWTLyKOzvY8abfpau6jATpvfBtvw2EaHyve6jhwae0B3jKo2nLuqDXcHDIE1pu59FZSdQ90N2C25LnXt8e60L8j368vX6j3efLytV8-b2HCedTHoAkDIIgPJ9TaTeSITk4kt14XmnHJWmlQLBhoZK8u0AKQMMS-pKGDLS8kXZDnm9abC2qqd7V2oy6vPoX819D_6Q9NhpQF4HIG9s389-k41lTdY17rF4ICCNJSSC04hSGGUGme9d1iqvasa7Y6KUTUMQV3-UOchBOjhlL_fNlhckLPr_B9X1IHQ |
| ContentType | Journal Article |
| Copyright | This work is licensed under a Creative Commons Attribution 4.0 International License. |
| Copyright_xml | – notice: This work is licensed under a Creative Commons Attribution 4.0 International License. |
| DBID | NPM AAYXX CITATION 7X8 GPN |
| DOI | 10.5935/0004-2749.20220088 |
| DatabaseName | PubMed CrossRef MEDLINE - Academic SciELO |
| DatabaseTitle | PubMed CrossRef MEDLINE - Academic |
| DatabaseTitleList | PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitleAlternate | O impacto do descolamento macular seroso na recuperação visual no tratamento de oclusões de veias retinianas |
| EISSN | 1678-2925 |
| EndPage | 613 |
| ExternalDocumentID | S0004_27492022000600606 10_5935_0004_2749_20220088 35170645 |
| Genre | Journal Article |
| GroupedDBID | 23N 2WC 53G 5GY 5VS 6J9 ABDHV ABXHO ACGFO ADBBV AEGXH AENEX AIAGR ALMA_UNASSIGNED_HOLDINGS APOWU AZFZN BAWUL BCNDV CS3 DIK E3Z EBD EBS EJD EMOBN F5P FIJ GROUPED_DOAJ GX1 IPNFZ KQ8 M~E NPM OK1 P2P RIG RNS RSC SCD SV3 XSB AAYXX C1A CITATION 7X8 GPN |
| ID | FETCH-LOGICAL-c337t-2ad2259d7293ab798494c75b3ada33031fc6a512ae11ff6d2e01ee8f05d2b3f93 |
| ISSN | 0004-2749 1678-2925 |
| IngestDate | Fri Oct 18 21:10:41 EDT 2024 Fri Jun 28 02:06:24 EDT 2024 Fri Aug 23 03:48:28 EDT 2024 Sat Sep 28 08:24:12 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Retinal vein occlusion Oclusão da veia retiniana Macular detachment Injeções intravítreas Intravitreal injections Descolamento macular Macular edema Edema macular |
| Language | English Portuguese |
| License | This work is licensed under a Creative Commons Attribution 4.0 International License. http://creativecommons.org/licenses/by/4.0 |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c337t-2ad2259d7293ab798494c75b3ada33031fc6a512ae11ff6d2e01ee8f05d2b3f93 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0003-1491-8659 |
| OpenAccessLink | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492022000600606&lng=en&tlng=en |
| PMID | 35170645 |
| PQID | 2629385302 |
| PQPubID | 23479 |
| PageCount | 8 |
| ParticipantIDs | scielo_journals_S0004_27492022000600606 proquest_miscellaneous_2629385302 crossref_primary_10_5935_0004_2749_20220088 pubmed_primary_35170645 |
| PublicationCentury | 2000 |
| PublicationDate | 2022-01-01 |
| PublicationDateYYYYMMDD | 2022-01-01 |
| PublicationDate_xml | – month: 01 year: 2022 text: 2022-01-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Brazil |
| PublicationPlace_xml | – name: Brazil |
| PublicationTitle | Arquivos brasileiros de oftalmologia |
| PublicationTitleAlternate | Arq Bras Oftalmol |
| PublicationYear | 2022 |
| Publisher | Conselho Brasileiro de Oftalmologia |
| Publisher_xml | – name: Conselho Brasileiro de Oftalmologia |
| References | Deobhakta, A; Chang, LK 2013; 2013 Bunt-Milam, AH; Saari, JC; Klock, IB; Garwin, GG 1985; 26 Dolz-Marco, R; Gallego-Pinazo, R; Sanz-Marco, E; Díaz-Llopis, M; Lleó-Pérez, A 2011; 86 Dib, E; Maia, M; Longo-Maugeri, IM; Martins, MC; Mussalem, JS; Squaiella, CC 2008; 49 Tsujikawa, A; Sakamoto, A; Ota, M; Kotera, Y; Oh, H; Miyamoto, K 2010; 149 Hayreh, SS 2005; 24 Balci, Ö; Öngör, E 2004; 34 Gallego-Pinazo, R; Dolz-Marco, R; Pardo-López, D; Martínez-Castillo, S; Lleó-Pérez, A; Arévalo, JF 2013; 251 Poon, YC; Chen, CH; Kuo, HK; Chen, YJ; Wu, PC; Chen, YH 2013; 29 Hoeh, AE; Ruppenstein, M; Ach, T; Dithmar, S 2010; 248 Marmor, MF 1985; 29 Catier, A; Tadayoni, R; Paques, M; Erginay, A; Haouchine, B; Gaudric, A 2005; 140 Spaide, RF; Lee, JK; Klancnik Jr, JK; Gross, NE 2003; 23 Daruich, A; Matet, A; Moulin, A; Kowalczuk, L; Nicolas, M; Sellam, A 2018; 63 Omri, S; Omri, B; Savoldelli, M; Jonet, L; Thillaye-Goldenberg, B; Thuret, G 2010; 4 Noma, H; Funatsu, H; Mimura, T; Tatsugawa, M; Shimada, K; Eguchi, S 2012; 32 1984; 98 Marmor, MF 1990; 4 Jaissle, GB; Szurman, P; Feltgen, N; Spitzer, B; Pielen, A; Rehak, M 2011; 249 Celık, E; Doğan, E; Turkoglu, EB; Çakır, B; Alagoz, G 2016; 79 Maggio, E; Polito, A; Guerriero, M; Pertile, G 2014; 232 Ohashi, H; Oh, H; Nishiwaki, H; Nonaka, A; Takagi, H 2004; 111 Park, SP; Ahn, JK; Mun, GH 2010; 30 Noma, H; Funatsu, H; Mimura, T; Shimada, K 2011; 11 Chung, EJ; Hong, YT; Lee, SC; Kwon, OW; Koh, HJ 2008; 246 Omri, S; Behar-Cohen, F; Rothschild, PR; Gélizé E, Jonet, L; Jeanny, JC 2013; 8 Shroff, D; Mehta, DK; Arora, R; Narula, R; Chauhan, D 2008; 28 Marmor, MF 1999; 97 |
| References_xml | – volume: 246 start-page: 1241 issue: 9 year: 2008 end-page: 1247 article-title: Prognostic factors for visual outcome after intravitreal bevacizumab for macular edema due to branch retinal vein occlusion publication-title: Graefes Arch Clin Exp Ophthalmol contributor: fullname: Chung, EJ; Hong, YT; Lee, SC; Kwon, OW; Koh, HJ – volume: 4 start-page: 340 issue: Pt 2 year: 1990 end-page: 344 article-title: Control of subretinal fluid: experimental and clinical studies publication-title: Eye (Lond) contributor: fullname: Marmor, MF – volume: 26 start-page: 1377 issue: 10 year: 1985 end-page: 1380 article-title: Zonulae adherentes pore size in the external limiting membrane of the rabbit retina publication-title: Invest Ophthalmol Vis Sci contributor: fullname: Bunt-Milam, AH; Saari, JC; Klock, IB; Garwin, GG – volume: 23 start-page: 343 issue: 3 year: 2003 end-page: 347 article-title: Optical coherence tomography of branch retinal vein occlusion publication-title: Retina contributor: fullname: Spaide, RF; Lee, JK; Klancnik Jr, JK; Gross, NE – volume: 248 start-page: 1567 issue: 11 year: 2010 end-page: 1572 article-title: OCT patterns of macular edema and response to bevacizumab therapy in retinal vein occlusion publication-title: Graefes Arch Clin Exp Ophthalmol contributor: fullname: Hoeh, AE; Ruppenstein, M; Ach, T; Dithmar, S – volume: 232 start-page: 207 issue: 4 year: 2014 end-page: 215 article-title: Intravitreal dexamethasone implant for macular edema secondary to retinal vein occlusion: 12-month follow-up and prognostic factors publication-title: Ophthalmologica contributor: fullname: Maggio, E; Polito, A; Guerriero, M; Pertile, G – volume: 24 start-page: 493 issue: 4 year: 2005 end-page: 519 article-title: Prevalent misconceptions about acute retinal vascular occlusive disorders publication-title: Prog Retin Eye Res contributor: fullname: Hayreh, SS – volume: 11 start-page: 29 issue: 1 year: 2011 end-page: 29 article-title: Visual function and serous retinal detachment in patients with branch retinal vein occlusion and macular edema: a case series publication-title: BMC Ophthalmol contributor: fullname: Noma, H; Funatsu, H; Mimura, T; Shimada, K – volume: 2013 start-page: 438412 year: 2013 end-page: 438412 article-title: Inflammation in retinal vein occlusion publication-title: Int J Inflamm contributor: fullname: Deobhakta, A; Chang, LK – volume: 32 start-page: 86 issue: 1 year: 2012 end-page: 91 article-title: Vitreous inflammatory factors and serous macular detachment in branch retinal vein occlusion publication-title: Retina contributor: fullname: Noma, H; Funatsu, H; Mimura, T; Tatsugawa, M; Shimada, K; Eguchi, S – volume: 251 start-page: 9 issue: 1 year: 2013 end-page: 14 article-title: Ranibizumab for serous macular detachment in branch retinal vein occlusions publication-title: Graefes Arch Clin Exp Ophthalmol contributor: fullname: Gallego-Pinazo, R; Dolz-Marco, R; Pardo-López, D; Martínez-Castillo, S; Lleó-Pérez, A; Arévalo, JF – volume: 111 start-page: 2050 issue: 11 year: 2004 end-page: 2056 article-title: Delayed absorption of macular edema accompanying serous retinal detachment after grid laser treatment in patients with branch retinal vein occlusion publication-title: Ophthalmology contributor: fullname: Ohashi, H; Oh, H; Nishiwaki, H; Nonaka, A; Takagi, H – volume: 28 start-page: 261 issue: 4 year: 2008 end-page: 268 article-title: Natural history of macular status in recent-onset branch retinal vein occlusion: an optical coherence tomography study publication-title: Int Ophthalmol contributor: fullname: Shroff, D; Mehta, DK; Arora, R; Narula, R; Chauhan, D – volume: 30 start-page: 281 issue: 2 year: 2010 end-page: 286 article-title: Aqueous vascular endothelial growth factor levels are associated with serous macular detachment secondary to branch retinal vein occlusion publication-title: Retina contributor: fullname: Park, SP; Ahn, JK; Mun, GH – volume: 34 start-page: 445 issue: 6 year: 2004 end-page: 455 article-title: Retinal Vein Occlusions publication-title: Turk J Ophthalmol contributor: fullname: Balci, Ö; Öngör, E – volume: 29 start-page: 131 issue: 2 year: 1985 end-page: 138 article-title: Barriers to fluorescein and protein movement publication-title: Jpn J Ophthalmol contributor: fullname: Marmor, MF – volume: 29 start-page: 319 issue: 3 year: 2013 end-page: 324 article-title: Clinical implications of serous retinal detachment in branch retinal vein occlusion and response after primary intravitreal bevacizumab injection publication-title: J Ocul Pharmacol Ther contributor: fullname: Poon, YC; Chen, CH; Kuo, HK; Chen, YJ; Wu, PC; Chen, YH – volume: 98 start-page: 271 issue: 3 year: 1984 end-page: 282 article-title: Argon laser photocoagulation for macular edema in branch vein occlusion publication-title: Am J Ophthalmol – volume: 79 start-page: 9 issue: 1 year: 2016 end-page: 11 article-title: Serous retinal detachment in patients with macular edema secondary to branch retinal vein occlusion publication-title: Arq Bras Oftalmol contributor: fullname: Celık, E; Doğan, E; Turkoglu, EB; Çakır, B; Alagoz, G – volume: 49 start-page: 1097 issue: 3 year: 2008 end-page: 1100 article-title: Subretinal bevacizumab detection after intravitreous injection in rabbits publication-title: Invest Ophthalmol Vis Sci contributor: fullname: Dib, E; Maia, M; Longo-Maugeri, IM; Martins, MC; Mussalem, JS; Squaiella, CC – volume: 97 start-page: 239 issue: 3-4 year: 1999 end-page: 249 article-title: Mechanisms of fluid accumulation in retinal edema publication-title: Doc Ophthalmol contributor: fullname: Marmor, MF – volume: 4 start-page: 183 year: 2010 end-page: 195 article-title: The outer limiting membrane (OLM) revisited: clinical implications publication-title: Clin Ophthalmol contributor: fullname: Omri, S; Omri, B; Savoldelli, M; Jonet, L; Thillaye-Goldenberg, B; Thuret, G – volume: 149 start-page: 291 issue: 2 year: 2010 end-page: 301 article-title: Serous retinal detachment associated with retinal vein occlusion publication-title: Am J Ophthalmol contributor: fullname: Tsujikawa, A; Sakamoto, A; Ota, M; Kotera, Y; Oh, H; Miyamoto, K – volume: 86 start-page: 335 issue: 10 year: 2011 end-page: 336 article-title: Influence of serous macular detachment on the efficacy of ranibizumab treatment in retinal vein occlusions publication-title: Arch Soc Esp Oftalmol contributor: fullname: Dolz-Marco, R; Gallego-Pinazo, R; Sanz-Marco, E; Díaz-Llopis, M; Lleó-Pérez, A – volume: 8 issue: 11 year: 2013 article-title: PKCζ mediates breakdown of outer blood-retinal barriers in diabetic retinopathy publication-title: PLoS One contributor: fullname: Omri, S; Behar-Cohen, F; Rothschild, PR; Gélizé E, Jonet, L; Jeanny, JC – volume: 249 start-page: 183 issue: 2 year: 2011 end-page: 192 article-title: Retinal Vein Occlusion Study Group. Predictive factors for functional improvement after intravitreal bevacizumab therapy for macular edema due to branch retinal vein occlusion publication-title: Graefes Arch Clin Exp Ophthalmol contributor: fullname: Jaissle, GB; Szurman, P; Feltgen, N; Spitzer, B; Pielen, A; Rehak, M – volume: 63 start-page: 20 year: 2018 end-page: 68 article-title: Mechanisms of macular edema: beyond the surface publication-title: Prog Retin Eye Res contributor: fullname: Daruich, A; Matet, A; Moulin, A; Kowalczuk, L; Nicolas, M; Sellam, A – volume: 140 start-page: 200 issue: 2 year: 2005 end-page: 206 article-title: Characterization of macular edema from various etiologies by optical coherence tomography publication-title: Am J Ophthalmol contributor: fullname: Catier, A; Tadayoni, R; Paques, M; Erginay, A; Haouchine, B; Gaudric, A |
| SSID | ssj0024995 |
| Score | 2.2813208 |
| Snippet | The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results.
A total of 117 eyes... PURPOSEThe aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results. METHODSA... ABSTRACT Purpose: The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results.... |
| SourceID | scielo proquest crossref pubmed |
| SourceType | Open Access Repository Aggregation Database Index Database |
| StartPage | 606 |
| SubjectTerms | OPHTHALMOLOGY |
| Title | Impact of serous macular detachment on visual recovery in retinal vein occlusion treatment |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/35170645 https://search.proquest.com/docview/2629385302 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492022000600606&lng=en&tlng=en |
| Volume | 85 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwELdgSNNepvFdBshISDxUgcZ2nPhxAqYNNIREJ028RLbjaBVtsrVJJfjruYvzUVaQAKmKWqf1Rfdzz3f2786EvAyNZdLGOgil0oFI8iQwcaYCqcHZFblIMoPJyWef5Mm5-HARXQwHFzbZJZV5bX_8Nq_kf1CFNsAVs2T_Adm-U2iA94AvXAFhuP4Vxqd9iiOIQy7rQntaKRJD7aXf5y_G69mqbur3W-RrfvcpLFVzHNbawYfS2nmNq2YD7XzTZz1aXtezdbkaQ2C9AiMyg4kVJIBYcNwXjfHsbfsxbts3dmf-raiX4ylMmwP_9zPE0ZUff5e62voNgN62tssQjG0sQzhvOmHaC5jyacw3DXOkeOSZjCKAOBgzhBgyL5LNL4NyrxYNVDzCqj6-zuSNctjdrdvkDotVhCzOd6cfh_KKSkU-NwpFvtkWuEd2uy5-dUW24gssHgv2db7pcEwPyH4bKdAjD_tdcssV98juWcuFuE--evRpmVOPPm3RpwP6tCyoR5926NNZQVv0KaJPe_Rpj_4Dcn78fvr2JGhPyggs53EVMJ2BXVYZREpcm1glQgkbR4brTHNwUsLcSg2unXZhmOcyY24SOpfkkyhjhueKPyQ7RVm4x4TiIbCGq9CAbRYxbrwbbWTijGExy5QYkXGntPTKF0RJIZBEbSORQaSo7bTT9oi86PSagt3CzShdOFBJyiQ8a4JnVo3II6_wvr8OoBF55RFI2z_dKv3Sy_AiJhJf8skf-zgke8NwfUp2qmXtnoEfWZnnzcj5CXixb40 |
| link.rule.ids | 230,315,786,790,891,27955,27956 |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Impact+of+serous+macular+detachment+on+visual+recovery+in+retinal+vein+occlusion+treatment&rft.jtitle=Arquivos+brasileiros+de+oftalmologia&rft.au=Firat%2C+Ilknur+Tuncer&rft.au=Polat%2C+Nihat&rft.au=Firat%2C+Murat&rft.date=2022-01-01&rft.eissn=1678-2925&rft_id=info:doi/10.5935%2F0004-2749.20220088&rft_id=info%3Apmid%2F35170645&rft.externalDocID=35170645 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0004-2749&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0004-2749&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0004-2749&client=summon |