Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis

• Published in: Stem cells and development Vol. 29; no. 23; p. 1520
• Main Authors: You, Jingyi, Zhou, Ou, Liu, Jiang, Zou, Wenjing, Zhang, Linghuan, Tian, Daiyin, Dai, Jihong, Luo, Zhengxiu, Liu, Enmei, Fu, Zhou, Zou, Lin
• Format: Journal Article
• Language: English
• Published: United States 01.12.2020
• Subjects: bronchopulmonary dysplasia; umbilical cord mesenchymal stem cells; extracellular vesicles

Bronchopulmonary dysplasia (BPD) is a serious chronic lung disease in premature newborns, with high morbidity and mortality rates. Mesenchymal stem cell (MSC) transplantation has developed into a promising approach to alleviate BPD. Small extracellular vesicles, which are an important therapeutic co...