Efficacy of galcanezumab in patients with chronic migraine and a history of preventive treatment failure

• Published in: Cephalalgia Vol. 39; no. 8; pp. 931 - 944
• Main Authors: Ruff, Dustin D, Ford, Janet H, Tockhorn-Heidenreich, Antje, Sexson, Matthew, Govindan, Sriram, Pearlman, Eric M, Wang, Shuu-Jiun, Khan, Arif, Aurora, Sheena K
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.07.2019
• Subjects: LY2951742; Galcanezumab; Phase 3 study; chronic migraine; preventive failure

Background Efficacy of galcanezumab in chronic migraine has been demonstrated in a pivotal Phase 3 study. Here, we assess efficacy in patients who have failed ≥2 and ≥1 prior migraine preventives for efficacy and/or safety reasons, and in those who never failed. Study design/methods REGAIN (NCT02614...