Overview of tandem mass spectrometry (MS/MS) database search algorithms

• Published in: Current protocols in protein science Vol. Chapter 25; p. 25.2.1
• Main Authors: Kapp, Eugene, Schütz, Frédéric
• Format: Journal Article
• Language: English
• Published: United States 01.08.2007
• Subjects: Algorithms; Databases, Protein; Tandem Mass Spectrometry - methods

Mass spectrometry-based methods for the identification of proteins are fundamental platform technologies for proteomics. One comprehensive approach is to subject trypsinized peptides to tandem mass spectrometry (MS/MS) to obtain detailed structural information. Different strategies are available for...