Safety and efficacy studies of liposomes in specific immunotherapy

• Published in: Current therapeutic research Vol. 60; no. 5; pp. 278 - 294
• Main Authors: Galvain, Sylvie, André, Claude, Vatrinet, Christine, Villet, Bertrand
• Format: Journal Article
• Language: English
• Published: Belle Mead, NJ EM Inc USA 01.05.1999; Excerpta medica
• Subjects: Biological and medical sciences; Dermatophagoides pteronyssinus; General pharmacology; grass pollens; Immunopathology; Immunotherapy (general aspects); liposome; Medical sciences; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; safety; specific immunotherapy; specific immunotherapy; grass pollens; safety; liposome; Dermatophagoides pteronyssinus; Encapsulation; Human; Delivery system; Prick test; Pharmaceutical technology; Healthy subject; Toxicity; Acaridida; Liposome; Intradermal administration; Acariformes; Arachnida; Acari; Efficiency; Arthropoda; Immunotherapy; Dosage form; Pyroglyphidae; Pollen; Invertebrata; Vector; Allergen
• ISSN: 0011-393X; 1879-0313
• DOI: 10.1016/S0011-393X(99)80004-6

Liposomes are lipid vesicles that have been extensively investigated because of their immunoadjuvant properties and their capacity to transport a variety of therapeutic agents. This article reports the results of 4 safety and efficacy studies of multilamellar liposomes used to incorporate an allerge...