Comparison of a sealed, polymer foam biodegradable temporizing matrix against Integra® dermal regeneration template in a porcine wound model

• Published in: Journal of burn care & research Vol. 33; no. 1; p. 163
• Main Authors: Greenwood, John Edward, Dearman, Bronwyn Louise
• Format: Journal Article
• Language: English
• Published: England 01.01.2012
• Subjects: Absorbable Implants; Animals; Chondroitin Sulfates; Collagen; Dermis - pathology; Dermis - surgery; Disease Models, Animal; Graft Rejection; Graft Survival; Immunohistochemistry; Polymers - therapeutic use; Random Allocation; Risk Factors; Skin Transplantation - adverse effects; Skin Transplantation - methods; Skin, Artificial; Swine; Wound Healing - physiology; Wounds and Injuries - pathology; Wounds and Injuries - surgery

The aim of this study is to develop and optimize the first stage of a proposed two-stage skin graft replacement strategy. This entails creation of a material that can be applied immediately after burn excision to "temporize" the wound bed, become integrated as a "neodermis," resi...