Effects of solvent and structure on the reactivity of 6-substituted nicotinic acids with diazodiphenylmethane in aprotic solvents

• Published in: Journal of the Serbian Chemical Society Vol. 74; no. 12; pp. 1359 - 1370
• Main Authors: Drmanic, Sasa, Marinkovic, Aleksandar, Jovanovic, Bratislav
• Format: Journal Article
• Language: English
• Published: Serbian Chemical Society 01.01.2009
• Subjects: aprotic solvents; diazodiphenylmethane; pyridine carboxylic acids; rate constants; solvatochromic parameters

The rate constants for the reactions of diazodiphenylmethane (DDM) with 6-substituted nicotinic acids in aprotic solvents at 30?C were determined. The obtained second order rate constants in aprotic solvents, together with literature data for benzoic and nicotinic acids in protic solvents, were used...