HIV vs. the Immune System: A Differential Game

• Published in: Mathematics (Basel) Vol. 3; no. 4; pp. 1139 - 1170
• Main Authors: Buratto, Alessandra, Cesaretto, Rudy, Zamarchi, Rita
• Format: Journal Article
• Language: English
• Published: MDPI AG 01.12.2015
• Subjects: acquired immunodeficiency syndrome (AIDS); differential games; human Immunodeficiency virus (HIV); mathematical modeling

A differential game is formulated in order to model the interaction between the immune system and the HIV virus. One player is represented by the immune system of a patient subject to a therapeutic treatment and the other player is the HIV virus. The aim of our study is to determine the optimal ther...