Synthesis of Imidazo[1,2‐a]pyridines: C‐H Functionalization in the Direction of C‐S Bond Formation

• Published in: Chemical record Vol. 17; no. 10; pp. 1019 - 1038
• Main Authors: Ravi, Chitrakar, Adimurthy, Subbarayappa
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.10.2017
• Subjects: Biological activity; Catalysis; Catalysts; C−S bond formations; Hydroamination; Imidazo [1, 2-a] pyridines; Intramolecular cyclization; Pyridines; Regioselectivity; Substrates; Synthesis; Intramolecular cyclization; C−S bond formations; Regioselectivity; Hydroamination; Imidazo [1, 2-a] pyridines

Imidazo[1,2‐a]pyridines play an important role in medicinal chemistry. In spite of very drastic developments on syntheses and functionalization in this area, the use of inexpensive catalysts and mild reaction conditions constitutes an important role in pharmaceutical applications. This account descr...