Leukotriene B4 production in healthy subjects carrying variants of the arachidonate 5-lipoxygenase-activating protein gene associated with a risk of myocardial infarction - Maznyczka, Annette; Mangino, Massimo; Whittaker, Andrew; Braund, Peter; Palmer, Tom; Tobin, Martin; Goodall, Alison H.; Bradding, Peter; Samani, Nilesh J. (Clinical science (1979), 2007)
Keywords: 5-Lipoxygenase-Activating Proteins; Analysis of Variance; Arachidonate 5-Lipoxygenase - metabolism; Biological and medical sciences; Calcimycin - pharmacology; Carrier Proteins - genetics; Carrier Proteins - metabolism; Cells, Cultured; Epidemiology; Female; General aspects; Genetic Predisposition to Disease; Haplotypes; Heterozygote; Humans; Ionophores - pharmacology; Leukotriene B4 - biosynthesis; Male; Medical sciences; Membrane Proteins - genetics; Membrane Proteins - metabolism; Middle Aged; Myocardial Infarction - genetics; Myocardial Infarction - metabolism; Neutrophils - drug effects; Neutrophils - metabolism; Polymorphism, Single Nucleotide; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Factors; Stimulation, Chemical; Myocardial infarction; Genetic variability; Healthy subject; Cardiovascular disease; Genotype; Risk; Myocardial disease; Epidemiology; Medicine; Variant; Association; Leukotriene B4; Heart disease; Risk factor; Production; ALOX5AP gene