Intercalation assembly of kojic acid into Zn-Ti layered double hydroxide with antibacterial and whitening performances
The inhibitor of melanin and the bacteriostatic agent kojic acid was inserted into Zn-Ti layered double hydroxide (LDH) by anion-exchange reaction. The structure, slow release, antibacterial and skin whitening activity were studied. [Display omitted] A melanin synthesis inhibitor and bacteriostatic...
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| Published in | Chinese chemical letters Vol. 30; no. 4; pp. 919 - 923 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
01.04.2019
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China%Department of Chemistry, Beijing Normal University, Beijing 100875, China |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-8417 1878-5964 |
| DOI | 10.1016/j.cclet.2019.03.050 |
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| Abstract | The inhibitor of melanin and the bacteriostatic agent kojic acid was inserted into Zn-Ti layered double hydroxide (LDH) by anion-exchange reaction. The structure, slow release, antibacterial and skin whitening activity were studied.
[Display omitted]
A melanin synthesis inhibitor and bacteriostatic agent, kojic acid (KA) has been intercalated into Zn-Ti layered double hydroxide (LDH) by an anion-exchange reaction. The structure and the thermal stability of the samples were characterized by XRD, FT-IR, TG-DTA and SEM. The study of KA release from ZnTi-KA-LDH in phosphate buffered solution (pH 5) implies that ZnTi-KA-LDH is a better controlled release system than pure KA. Meanwhile, the mechanisms of slow release were assessed by using four commonly kinetic models. The antimicrobial activity of ZnTi-KA-LDH was tested against three kinds of bacteria. The inhibition of l-dopa oxidation was tested to verify its skin whitening effect. The studies suggest that the kojic acid intercalated LDHs has the potential application as a safely functional composite in cosmetic. |
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| AbstractList | A melanin synthesis inhibitor and bacteriostatic agent, kojic acid (KA) has been intercalated into Zn-Ti layered double hydroxide (LDH) by an anion-exchange reaction. The structure and the thermal stability of the samples were characterized by XRD, FT-IR, TG-DTA and SEM. The study of KA release from ZnTi-KA-LDH in phosphate buffered solution (pH 5) implies that ZnTi-KA-LDH is a better controlled release system than pure KA. Meanwhile, the mechanisms of slow release were assessed by using four commonly kinetic models. The antimicrobial activity of ZnTi-KA-LDH was tested against three kinds of bacteria. The inhibition of L-dopa oxidation was tested to verify its skin whitening effect. The studies suggest that the kojic acid intercalated LDHs has the potential application as a safely functional composite in cosmetic. The inhibitor of melanin and the bacteriostatic agent kojic acid was inserted into Zn-Ti layered double hydroxide (LDH) by anion-exchange reaction. The structure, slow release, antibacterial and skin whitening activity were studied. [Display omitted] A melanin synthesis inhibitor and bacteriostatic agent, kojic acid (KA) has been intercalated into Zn-Ti layered double hydroxide (LDH) by an anion-exchange reaction. The structure and the thermal stability of the samples were characterized by XRD, FT-IR, TG-DTA and SEM. The study of KA release from ZnTi-KA-LDH in phosphate buffered solution (pH 5) implies that ZnTi-KA-LDH is a better controlled release system than pure KA. Meanwhile, the mechanisms of slow release were assessed by using four commonly kinetic models. The antimicrobial activity of ZnTi-KA-LDH was tested against three kinds of bacteria. The inhibition of l-dopa oxidation was tested to verify its skin whitening effect. The studies suggest that the kojic acid intercalated LDHs has the potential application as a safely functional composite in cosmetic. |
| Author | Gao, Xue-Wei Li, Shu-Jing Cao, Xue-Li Wang, Xin-Rui Yan, Dongpeng Zhou, Wei Cheng, Hui-Min |
| AuthorAffiliation | Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China%Department of Chemistry, Beijing Normal University, Beijing 100875, China |
| AuthorAffiliation_xml | – name: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China%Department of Chemistry, Beijing Normal University, Beijing 100875, China |
| Author_xml | – sequence: 1 givenname: Xin-Rui surname: Wang fullname: Wang, Xin-Rui organization: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China – sequence: 2 givenname: Hui-Min surname: Cheng fullname: Cheng, Hui-Min organization: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China – sequence: 3 givenname: Xue-Wei surname: Gao fullname: Gao, Xue-Wei organization: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China – sequence: 4 givenname: Wei orcidid: 0000-0002-0590-9163 surname: Zhou fullname: Zhou, Wei organization: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China – sequence: 5 givenname: Shu-Jing surname: Li fullname: Li, Shu-Jing organization: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China – sequence: 6 givenname: Xue-Li orcidid: 0000-0001-9160-1511 surname: Cao fullname: Cao, Xue-Li email: caoxli@th.btbu.edu.cn organization: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China – sequence: 7 givenname: Dongpeng surname: Yan fullname: Yan, Dongpeng email: yandp@bnu.edu.cn organization: Department of Chemistry, Beijing Normal University, Beijing 100875, China |
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| Snippet | The inhibitor of melanin and the bacteriostatic agent kojic acid was inserted into Zn-Ti layered double hydroxide (LDH) by anion-exchange reaction. The... A melanin synthesis inhibitor and bacteriostatic agent, kojic acid (KA) has been intercalated into Zn-Ti layered double hydroxide (LDH) by an anion-exchange... |
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| SubjectTerms | Antimicrobial Intercalation Kojic acid Layered double hydroxide Slow release Tyrosinase |
| Title | Intercalation assembly of kojic acid into Zn-Ti layered double hydroxide with antibacterial and whitening performances |
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