A new chalcone from the aerial roots of Ficus microcarpa

A new flavonoid with chalcone skeleton was isolated from the dried aerial roots of Ficus microcarpa. The structure of the compound was elucidated on the basis of spectral methods including 1D and 2D NMR. The new compound showed weak inhibitory effect on nitric oxide production and cytotoxicity again...

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Bibliographic Details
Published inChinese chemical letters Vol. 20; no. 5; pp. 576 - 578
Main Authors Xu, Hui, Wang, Xiang Min, Wei, Xing, Li, Jing Yuan, Liu, Ke
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.05.2009
Shandong Target Drug Research Co.Ltd,Yantai 264006,China
School of Pharmacy,Yantai University,Yantai 264005,China%Shandong Target Drug Research Co.Ltd,Yantai 264006,China%School of Pharmacy,Yantai University,Yantai 264005,China
Subjects
Aerial roots
Chalcone
Cytotoxicity
Ficus microcarpa
Nitric oxide (NO) release
Nitric oxide (NO) release
Cytotoxicity
Aerial roots
Ficus microcarpa
Chalcone
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Summary:A new flavonoid with chalcone skeleton was isolated from the dried aerial roots of Ficus microcarpa. The structure of the compound was elucidated on the basis of spectral methods including 1D and 2D NMR. The new compound showed weak inhibitory effect on nitric oxide production and cytotoxicity against K562 and PC3 cells.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2009.01.013