Microwave-assisted Quaternization of Various Pyridine Derivatives and their Antibacterial Activity

• Published in: Croatica Chemica Acta Vol. 90; no. 3; p. 425
• Main Authors: Bušić, Valentina, Pavlović, Hrvoje, Roca, Sunčica, Vikić-Topić, Dražen, Gašo-Sokač, Dajana
• Format: Journal Article Paper
• Language: English
• Published: Croatica Chemica Acta 01.12.2017; Hrvatsko kemijsko društvo
• Subjects: antibacterial activity; Chemical properties; Chemical reactions; microwave synthesis; Microwaves; NMR; Observations; Pyridine; pyridine derivatives; quaternization

In this study, reactions of quaternization under microwave heating of pyridine, [alpha]-picoline, pyridine-4-aldoxime, pyridine-2-aldoxime, nicotinamide, isonicotinamide and pyridoxal oxime with different electrophiles: 2-bromo-4'-nitroacetophenone, 2-amino-4-chloro-methylthiazole hydrochloride...