Pre-exposure Prophylaxis: Clinical Considerations for Overcoming Barriers to Uptake and Persistence
AbstractPre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention is an essential part of the ending the HIV epidemic strategy. Currently, there are 4 guideline-approved dosing approaches to PrEP, w...
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| Published in | The Journal of the Association of Nurses in AIDS Care Vol. 36; no. 3; pp. 315 - 322 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Philadelphia, PA
Wolters Kluwer
01.05.2025
Lippincott Williams & Wilkins Ovid Technologies |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1055-3290 1552-6917 1552-6917 |
| DOI | 10.1097/JNC.0000000000000549 |
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| Abstract | AbstractPre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention is an essential part of the ending the HIV epidemic strategy. Currently, there are 4 guideline-approved dosing approaches to PrEP, which include 2 oral formulations and 1 long-acting injectable. Unfortunately, most individuals who would benefit from PrEP do not receive a prescription, and even fewer initiate and continue PrEP. Barriers to PrEP uptake and persistence are complex and extend along a socio-ecologic framework from individual through structural. In this article, we highlight the barriers to PrEP care among priority populations, discuss evidence-based solutions, and offer multilevel considerations for clinicians, researchers, and community members to increase access, uptake, and persistence in PrEP care for all. |
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| AbstractList | Pre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention is an essential part of the ending the HIV epidemic strategy. Currently, there are 4 guideline-approved dosing approaches to PrEP, which include 2 oral formulations and 1 long-acting injectable. Unfortunately, most individuals who would benefit from PrEP do not receive a prescription, and even fewer initiate and continue PrEP. Barriers to PrEP uptake and persistence are complex and extend along a socio-ecologic framework from individual through structural. In this article, we highlight the barriers to PrEP care among priority populations, discuss evidence-based solutions, and offer multilevel considerations for clinicians, researchers, and community members to increase access, uptake, and persistence in PrEP care for all. AbstractPre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention is an essential part of the ending the HIV epidemic strategy. Currently, there are 4 guideline-approved dosing approaches to PrEP, which include 2 oral formulations and 1 long-acting injectable. Unfortunately, most individuals who would benefit from PrEP do not receive a prescription, and even fewer initiate and continue PrEP. Barriers to PrEP uptake and persistence are complex and extend along a socio-ecologic framework from individual through structural. In this article, we highlight the barriers to PrEP care among priority populations, discuss evidence-based solutions, and offer multilevel considerations for clinicians, researchers, and community members to increase access, uptake, and persistence in PrEP care for all. Pre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention is an essential part of the ending the HIV epidemic strategy. Currently, there are 4 guideline-approved dosing approaches to PrEP, which include 2 oral formulations and 1 long-acting injectable. Unfortunately, most individuals who would benefit from PrEP do not receive a prescription, and even fewer initiate and continue PrEP. Barriers to PrEP uptake and persistence are complex and extend along a socio-ecologic framework from individual through structural. In this article, we highlight the barriers to PrEP care among priority populations, discuss evidence-based solutions, and offer multilevel considerations for clinicians, researchers, and community members to increase access, uptake, and persistence in PrEP care for all.ABSTRACTPre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention is an essential part of the ending the HIV epidemic strategy. Currently, there are 4 guideline-approved dosing approaches to PrEP, which include 2 oral formulations and 1 long-acting injectable. Unfortunately, most individuals who would benefit from PrEP do not receive a prescription, and even fewer initiate and continue PrEP. Barriers to PrEP uptake and persistence are complex and extend along a socio-ecologic framework from individual through structural. In this article, we highlight the barriers to PrEP care among priority populations, discuss evidence-based solutions, and offer multilevel considerations for clinicians, researchers, and community members to increase access, uptake, and persistence in PrEP care for all. |
| Author | Leonard, Adam Bergman, Alanna J. Albright, Nathaniel |
| Author_xml | – sequence: 1 givenname: Nathaniel orcidid: 0000-0001-7213-185X surname: Albright fullname: Albright, Nathaniel organization: Alanna J. Bergman, PhD, MSN, AGPCNP, is a postdoctoral fellow, University of Virginia School of Nursing, Charlottesville, Virginia, USA – sequence: 2 givenname: Adam orcidid: 0000-0003-1121-6993 surname: Leonard fullname: Leonard, Adam organization: Alanna J. Bergman, PhD, MSN, AGPCNP, is a postdoctoral fellow, University of Virginia School of Nursing, Charlottesville, Virginia, USA – sequence: 3 givenname: Alanna J. orcidid: 0000-0003-1474-7765 surname: Bergman fullname: Bergman, Alanna J. email: dhm8ax@virginia.edu organization: Alanna J. Bergman, PhD, MSN, AGPCNP, is a postdoctoral fellow, University of Virginia School of Nursing, Charlottesville, Virginia, USA |
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| Keywords | access barrier PrEP HIV youth women |
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| Score | 2.3767536 |
| Snippet | AbstractPre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical... Pre-exposure prophylaxis (PrEP) is the administration of antiretroviral medications before HIV exposure to prevent HIV infection. PrEP or biomedical prevention... |
| SourceID | proquest pubmed crossref wolterskluwer |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 315 |
| SubjectTerms | Anti-HIV Agents - administration & dosage Anti-HIV Agents - therapeutic use Antiretroviral therapy Barriers Dosage Epidemics Health Services Accessibility HIV HIV Infections - drug therapy HIV Infections - prevention & control Human immunodeficiency virus Humans Medication Adherence Patient Acceptance of Health Care Pre-Exposure Prophylaxis - methods Uptake |
| Title | Pre-exposure Prophylaxis: Clinical Considerations for Overcoming Barriers to Uptake and Persistence |
| URI | https://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&DO=10.1097/JNC.0000000000000549 https://www.ncbi.nlm.nih.gov/pubmed/40197976 https://www.proquest.com/docview/3194117584 https://www.proquest.com/docview/3187530043 |
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