Expression and clinical significance of Klotho protein in serum, umbilical cord blood, and placenta of pregnant women with intrauterine growth restriction

• Published in: Frontiers in pediatrics Vol. 13; p. 1611877
• Main Authors: Zeng, Guixiang, Lian, Jingjing, Shen, Jiajia, Shi, Yuan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2025
• Subjects: growth hormone; insulin-like growth factor-1; intrauterine growth restriction; Klotho; Pediatrics; placenta; intrauterine growth restriction; insulin-like growth factor-1; placenta; growth hormone; Klotho

Intrauterine growth restriction (IUGR) significantly affects neonatal development, but its pathogenesis is not fully understood. Klotho protein is involved in aging-related diseases, and its role in fetal growth is unclear. This study aims to explore Klotho's role in IUGR. A case-control study...