Electrocardiographic abnormalities among late-stage non-dialysis chronic kidney disease patients

• Published in: Journal of basic and clinical physiology and pharmacology Vol. 32; no. 3; pp. 155 - 162
• Main Authors: Mulia, Eka P.B., Nugraha, Ricardo A., A’yun, Maya Q., Juwita, Rahima R., Yofrido, Filipus M., Julario, Rerdin, Alkaff, Firas F.
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 01.05.2021; Walter de Gruyter GmbH
• Subjects: cardiovascular disease; chronic kidney diseases; electrocardiogram; Kidney diseases; chronic kidney diseases; cardiovascular disease; electrocardiogram
• ISSN: 0792-6855; 2191-0286
• DOI: 10.1515/jbcpp-2020-0068

Cardiovascular disease (CVD) complication is common among chronic kidney disease (CKD) patients. Thus, knowledge about CVD and ECG abnormalities in CKD are essential due to progressive nature of the disease and increased risk of sudden cardiac death. This study aims to scrutinize the ECG abnormalities among nondialysis late-stage CKD patients. A descriptive observational study was conducted at Dr. Soetomo General Hospital, Surabaya, Indonesia. Subjects were hospitalized patients with late-stage CKD between 1 January and 31 December 2019, who were consulted at the department of cardiology and vascular medicine during their initial admission at emergency room. ECG interpretation for this study was done by qualified cardiologist. There were 191 patients included in this study. Mean ages were 52.2 ± 11.8 years old and 51% were males. Total 143 (74.9%) patients had anemia, 111 (58.1%) had hypertension and 75 (39.3%) had type 2 diabetes mellitus. Mean serum creatinine was 10.5 ± 8.0 mg/dL. There were 176 (92.1%) patients with at least one form of ECG abnormalities. Prolonged QTc interval (36.6%), fragmented QRS complex (29.8%), poor R wave progression (24.6%), peaked T wave (22.0%) and left ventricular hypertrophy (16.7%) were the most common abnormalities. ECG abnormalities are common among nondialysis late-stage CKD patients. Given the fact that long-term CKD influences the pathogenesis cardiovascular diseases and substantial cardiovascular mortality, there is a need to screen Indonesian CKD patients who are at risks of getting earlier complications.