Self-organized optimal packing of kinesin-5-driven microtubule asters scales with cell size

• Published in: Journal of cell science Vol. 134; no. 10
• Main Authors: Khetan, Neha, Pruliere, Gérard, Hebras, Celine, Chenevert, Janet, Athale, Chaitanya A.
• Format: Journal Article
• Language: English
• Published: Company of Biologists 15.05.2021
• Subjects: Life Sciences; kinesin-5; scaling; aster; self-organization; Microtubule; tessellation

Radial microtubule (MT) arrays or asters determine cell geometry in animal cells. Multiple asters interacting with motors, such as those in syncytia, form intracellular patterns, but the mechanical principles behind this are not clear. Here, we report that oocytes of the marine ascidian Phallusia ma...