Assessment of apoptotic cell phagocytosis by macrophages

• Published in: Methods in molecular biology (Clifton, N.J.) Vol. 559; p. 247
• Main Authors: McPhillips, Kathleen A, Erwig, Lars-Peter
• Format: Journal Article
• Language: English
• Published: United States 2009
• Subjects: Animals; Apoptosis; Cytological Techniques; Humans; Macrophages - cytology; Neutrophils - cytology; Phagocytosis

Cells undergo apoptosis during development, tissue homeostasis, and disease, and are rapidly cleared by both professional and nonprofessional phagocytes. In the whole animal, this process is remarkably efficient and usually goes unnoticed. It is estimated that 2 x 10(11) cells are cleared each day a...