Genetic profile for the detection of susceptibility to poisoning by exposure to pesticides

• Published in: Annals of Agricultural and Environmental Medicine Vol. 28; no. 2; pp. 208 - 213
• Main Authors: Ceja Galvez, Hazael, Salazar Flores, Joel, Torres Sanchez, Erandis, Rojas Bravo, Daniel, Reyna Villela, Mireya Zoila, Reyes Uribe, Emmanuel
• Format: Journal Article
• Language: English
• Published: Lublin Institute of Rural Health 01.01.2021
• Subjects: Deoxyribonucleic acid; DNA; DNA repair; Enzymes; Gene polymorphism; Glutathione transferase; Literature reviews; OGG1 protein; Oxidative metabolism; Oxidative stress; Pesticides; Poisoning; Single-nucleotide polymorphism; Superoxide dismutase; Susceptibility; XRCC1 protein

Introduction: In humans, there are sets of genes that encode enzymes that decrease or increase the risks derived from exposure to pesticides. These include DNA repair genes (XRCC1, OGG1 and XRCC4); pesticide metabolizers (GSTP1 and PON1), and genes that act against oxidative stress (SOD2 and NQO1)....